4-Chloropyridine-2-carbonyl Chloride Hydrochloride - Names and Identifiers
4-Chloropyridine-2-carbonyl Chloride Hydrochloride - Physico-chemical Properties
Molecular Formula | C6H4Cl3NO
|
Molar Mass | 212.46 |
Melting Point | 135-137°C (dec.) |
Storage Condition | -20°C Freezer, Under Inert Atmosphere |
4-Chloropyridine-2-carbonyl Chloride Hydrochloride - Introduction
The Chloride Hydrochloride is an organic compound with the chemical formula C6H4Cl2NClH. The following is an introduction to its nature, use, preparation and safety information:
1. nature:
-Appearance: colorless crystalline powder
-Solubility: Soluble in chloroform, dimethyl sulfoxide and methanol, slightly soluble in ethanol and ether
-Melting point: about 130-133°C
-Density: 1.48 g/mL
-Molecular weight: 199.47g/mol
2. use:
Chloride Hydrochloride is an important intermediate in organic synthesis and is often used in the synthesis of drugs and pesticides.
-It can be used to synthesize various pyridine compounds and other important intermediates in organic synthesis.
3. Preparation method:
The preparation of Chloride Hydrochloride is generally carried out by the following reactions:
-First, 4-chloropyridine and formic acid chloride are reacted to obtain 4-chloropyridine-2-carboxylic acid chloride.
-Then, the obtained 4-chloropyridine-2-carboxylic acid chloride is reacted with hydrochloric acid to obtain Chloride Hydrochloride.
4. Safety Information:
Chloride Hydrochloride is an organochlorine compound, which is irritating and corrosive. So in the use and operation need to pay attention to the following matters:
-Avoid direct contact with skin and eyes and use personal protective equipment.
-Operate in a well-ventilated place to avoid inhaling its vapors and powders.
-It should be sealed when stored, away from high temperature and fire sources.
-Collision and friction may cause fire and should be avoided.
-Follow proper laboratory procedures during processing.
Last Update:2024-04-09 21:04:16