4-FLUOROPHENYL-4-PYRIDYLMETHYL KETONE - Names and Identifiers
4-FLUOROPHENYL-4-PYRIDYLMETHYL KETONE - Physico-chemical Properties
Molecular Formula | C13H10FNO
|
Molar Mass | 215.22 |
Density | 1.201±0.06 g/cm3(Predicted) |
Melting Point | 94-97 °C |
Boling Point | 362.6±22.0 °C(Predicted) |
Flash Point | 173.1°C |
Vapor Presure | 1.91E-05mmHg at 25°C |
pKa | 5.18±0.10(Predicted) |
Storage Condition | Sealed in dry,Room Temperature |
Refractive Index | 1.571 |
4-FLUOROPHENYL-4-PYRIDYLMETHYL KETONE - Introduction
1-(4-fluorophenyl)-2-pyridin-4-ylethanone, also known as 1-(4-fluorophenyl)-2-pyridyl ethanone, is an organic compound. Its molecular formula is C13H10FNO and its relative molecular mass is 221.22. Its appearance is white to light yellow crystals or powder.
One of the main uses of 1-(4-fluorophenyl)-2-pyridin-4-ylethanone is as an intermediate in organic synthesis. It can be used to synthesize physiologically active compounds such as pharmaceuticals and pesticides. In addition, it can also be applied to the synthesis of dyes and dye intermediates.
The method of preparing 1-(4-fluorophenyl)-2-pyridin-4-ylethanone generally includes the following steps:
1. Under acidic conditions, 1-(4-pyridyl)-2-benzoyl chloride is prepared by reacting benzoyl chloride with pyridine.
2. The addition reaction of hydrogen cyanide converts 1-(4-pyridyl)-2-benzoyl chloride into 1-(4-pyridyl)-2-benzoyl acetonitrile.
3. Finally, 1-(4-pyridyl)-2-benzoylacetonitrile is reacted with fluorobenzoyl borate to obtain the final product 1-(4-fluorophenyl)-2-pyridin-4-ylethanone.
For safety information, the specific toxicity, risk and safety guidelines for 1-(4-fluorophenyl)-2-pyridin-4-ylethanone depend on the specific application and content. When handling and using chemicals, follow safe operating procedures and proper personal protective measures. Refer to the relevant Safety Data Sheet (SDS) or consult a chemical professional before use.
Last Update:2024-04-09 21:00:56