4-Fluoro-2-formyltoluene, 5-Fluoro-o-tolualdehyde
5-Fluoro-2-methylbenzaldehyde
CAS: 22062-53-9
Molecular Formula: C8H7FO
4-Fluoro-2-formyltoluene, 5-Fluoro-o-tolualdehyde - Names and Identifiers
| Name | 5-Fluoro-2-methylbenzaldehyde |
| Synonyms | VHR CF F1 5-FLUORO-2-METHYLBENZALDEHYDE 5-Fluoro-2-methylbenzaldehyde Benzaldehyde, 5-fluoro-2-methyl- 5-Fluoro-2-methylbenzaldehyde Jrd-1638 4-Fluoro-2-formyltoluene, 5-Fluoro-o-tolualdehyde |
| CAS | 22062-53-9 |
| InChI | InChI=1/C8H7FO/c1-6-2-3-8(9)4-7(6)5-10/h2-5H,1H3 |
4-Fluoro-2-formyltoluene, 5-Fluoro-o-tolualdehyde - Physico-chemical Properties
| Molecular Formula | C8H7FO |
| Molar Mass | 138.14 |
| Density | 1.1446 g/mL at 25 °C |
| Boling Point | 99°C/30mmHg(lit.) |
| Flash Point | 77°C |
| Vapor Presure | 0.378mmHg at 25°C |
| Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
| Sensitive | Air Sensitive |
| Refractive Index | 1.5244 |
4-Fluoro-2-formyltoluene, 5-Fluoro-o-tolualdehyde - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R41 - Risk of serious damage to eyes |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S39 - Wear eye / face protection. |
| WGK Germany | 3 |
| HS Code | 29130000 |
4-Fluoro-2-formyltoluene, 5-Fluoro-o-tolualdehyde - Reference Information
| preparation | p-fluorotoluene is added to the three-mouth bottle equipped with a stirrer and a constant pressure drop funnel, with anhydrous and oxygen-free operation, nitrogen protection, slow drop of tert-butyl lithium under ice bath, and the drop is completed within 1 hour. Reaction for 1 hour, thin layer chromatography to detect the progress of the reaction. DMF was added slowly, the addition was completed within 15 minutes, the reaction was performed under ice bath for 2 hours, and the reaction progress was detected by thin layer chromatography. Add saturated ammonium chloride solution to quench, dichloromethane extraction, wash the organic layer with water, dry with anhydrous sodium sulfate, and concentrate into colorless to light yellow liquid 5-fluoro-2-methylbenzaldehyde. |
Last Update：2024-04-09 21:04:16
