4-HYDROXY-3-AMINOBENZENE SULFONAMIDE

4-HYDROXY-3-AMINOBENZENE SULFONAMIDE - Names and Identifiers

Name	2-Aminophenol-5-sulfamide
Synonyms	222-729-5 4-HYDROXYMETANILAMIDE 2-Aminophenol-5-sulfamide 2-AMINOPHENOL-4-SULFOAMINE 2-AMINOPHENOL-4-SULFONAMIDE 2-AMINOPHENOL-4-SULFONYL AMIDE 4-Amino-3-hydroxybenzenesulfonamide 3-AMINO-4-HYDROXYBENZENESULFONAMIDE 4-HYDROXY-3-AMINOBENZENE SULFONAMIDE 4-amino-3-hydroxybenzenesulphonamide benzenesulfonamide, 4-amino-3-hydroxy- Benzenesulfonamide, 4-amino-3-hydroxy- (9CI)
CAS	3588-76-9
EINECS	222-729-5
InChI	InChI=1/C6H8N2O3S/c7-5-2-1-4(3-6(5)9)12(8,10)11/h1-3,9H,7H2,(H2,8,10,11)

4-HYDROXY-3-AMINOBENZENE SULFONAMIDE - Physico-chemical Properties

Molecular Formula	C6H8N2O3S
Molar Mass	188.2
Density	1.580
Melting Point	164 °C
Boling Point	451.5±55.0 °C(Predicted)
Flash Point	226.9°C
Vapor Presure	9.05E-09mmHg at 25°C
pKa	8.66±0.10(Predicted)
Storage Condition	4°C, Inert atmosphere
Refractive Index	1.667

4-HYDROXY-3-AMINOBENZENE SULFONAMIDE - Introduction

2-Aminophenol-5-sulfonamide, also known as 2-aminophenol-5-sulfonamide, is an organic compound. Its chemical formula is C6H8N2O3S and its molecular weight is 188.2g/mol. The following is a description of the properties, uses, preparation and safety information of the compound:

Nature:
-Appearance: White crystalline powder
-Melting point: about 180-181°C
-Soluble: Soluble in acid, slightly soluble in water and ethanol

Use:
-Chemical reagent: It can be used as an intermediate for dyes, fluorescent dyes and indicators, and is widely used in organic synthesis.
-Drug: 2-Aminophenol-5-sulfamide has antibiotic activity and can be used to synthesize drugs.

Preparation Method:
- 2-Aminophenol-5-sulfamide can be obtained by sulfonation of aniline on heptanone. The specific step is to first react aniline with nitrosoamine to produce heptanone, and then carry out sulfonation reaction to produce the target product.

Safety Information:
- 2-Aminophenol-5-sulfamide is a general organic compound, and its toxicity should be noted. When handling, wear protective gloves, glasses, and a protective mask to avoid contact, inhalation, or ingestion. It should be operated in a well-ventilated place and away from fire and flammable materials. In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical treatment.

Last Update：2024-04-09 02:00:45