4-Hydroxymethyl-1-methylpyrazole

4-Hydroxymethyl-1-methylpyrazole - Names and Identifiers

Name	4-Hydroxymethyl-1-methylpyrazole
Synonyms	(1-Methyl-1H-pyrazol-4-yl... (1-methylpyrazol-4-yl)methanol (1-methyl-4-pyrazolyl)methanol 1-Methyl-1H-pyrazole-4-methanol 4-Hydroxymethyl-1-methylpyrazole 1H-pyrazole-4-methanol, 1-methyl- (1-methyl-1H-pyrazol-4-yl)methanol
CAS	112029-98-8
InChI	InChI=1/C5H8N2O/c1-7-3-5(4-8)2-6-7/h2-3,8H,4H2,1H3

4-Hydroxymethyl-1-methylpyrazole - Physico-chemical Properties

Molecular Formula	C5H8N2O
Molar Mass	112.13
Density	1.16
Melting Point	101℃
Boling Point	244 °C
Flash Point	101 °C
Vapor Presure	0.017mmHg at 25°C
pKa	14.10±0.10(Predicted)
Storage Condition	2-8°C
Refractive Index	1.552
MDL	MFCD01822311

4-Hydroxymethyl-1-methylpyrazole - Risk and Safety

Hazard Class

IRRITANT

4-Hydroxymethyl-1-methylpyrazole - Introduction

1-Methyl-4-hydroxymethylpyrazole is an organic compound with the chemical formula C6H7NO2. It has the appearance of a white crystalline solid and has a peculiar smell. The following is a description of some properties, uses, preparation and safety information about 1-methyl -4-hydroxymethyl pyrazole:

Nature:
1-Methyl-4-hydroxymethylpyrazole is a water-soluble compound, soluble in many organic solvents such as alcohols and ethers. It is a stable compound, but it may decompose under the action of light. It has a density of 1.22g/cm³ and a melting point of 125-126°C. It is more stable under acidic conditions, but decomposes under alkaline conditions.

Use:
1-methyl -4-hydroxymethyl pyrazole has a wide range of uses in the field of chemistry. It is a commonly used chemical intermediate for the synthesis of many drugs and pesticides. It can also be used to synthesize chemicals such as antimicrobials, dyes and coatings. In addition, it is used as a fungicide and wood preservative.

Preparation Method:
A conventional method for producing 1-methyl-4-hydroxymethylpyrazole is obtained by condensation reaction of p-methylpyrazole with formaldehyde. This reaction is usually carried out under basic conditions, usually with an alcohol or ether as solvent. During the preparation process, care should be taken to control the reaction temperature and time to ensure yield and purity.

Safety Information:
1-Methyl-4-hydroxymethylpyrazole is relatively safe under general handling conditions. However, as a chemical, it may have irritating effects on the skin, eyes and respiratory system. Therefore, wear appropriate protective equipment such as gloves, goggles and respiratory protection when using or touching it. During storage and handling, contact with oxidants, strong acids and strong bases should be avoided. At the same time, avoid inhaling its vapor and dust to avoid adverse health effects. Local environmental treatment and disposal procedures should be followed when disposing of waste. To ensure safety, 1-methyl-4-hydroxymethylpyrazole should be used subject to proper handling and laboratory safety guidelines.

Last Update：2024-04-09 21:11:58