Name | 4-Hydroxypiperidine |
Synonyms | 4PPOL 4-PIPERIDIOL 4-PIPERIDINOL 4-Piperidinol 4-piperidinyl AURORA KA-1006 piperidin-4-ol PIPERIDIN-4-OL 4-Hydroxypiperidine 4-HYDROXYPIPERIDINE 4-Hydroxypipertidine 4-Hydroxy Piperidine 4-hydroxypiperidinium HYDROXYPIPERIDINE(4-) Hydroxypiperidine, 4- 4-Hydroxypiperidine base N-(4-Chiorobenzyl)-piperidonel N-(4-Chiorobenzyl)-4-piperidone |
CAS | 5382-16-1 |
EINECS | 226-373-1 |
InChI | InChI=1/C5H11NO/c7-5-1-3-6-4-2-5/h5-7H,1-4H2/p+1 |
InChIKey | HDOWRFHMPULYOA-UHFFFAOYSA-N |
Molecular Formula | C5H11NO |
Molar Mass | 101.15 |
Density | 0.9903 (rough estimate) |
Melting Point | 86-90°C |
Boling Point | 108-114 °C/10 mmHg (lit.) |
Flash Point | 226°F |
Water Solubility | soluble |
Solubility | Chloroform (Slightly), Methanol (Slightly) |
Vapor Presure | 13Pa at 25℃ |
Appearance | Yellow solid |
Color | Off-White to pale Yellow |
BRN | 102738 |
pKa | 14.94±0.20(Predicted) |
PH | 11.5-11.7 (H2O)Aqueous solution |
Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
Sensitive | Hygroscopic |
Refractive Index | 1.4400 (estimate) |
MDL | MFCD00005999 |
Use | N-anti-O-arylation for copper catalysis |
Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R34 - Causes burns |
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S37/39 - Wear suitable gloves and eye/face protection S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S27 - Take off immediately all contaminated clothing. |
UN IDs | 3263 |
WGK Germany | 3 |
HS Code | 29333999 |
Hazard Note | Irritant |
Hazard Class | 8 |
Packing Group | III |
LogP | -0.35 at 25℃ |
NIST chemical information | Information provided by: webbook.nist.gov (external link) |
use | 4-hydroxypiperidine can be used in copper-catalyzed N-anti-O-arylation, and can also be used as a pharmaceutical intermediate, ebastine, nafofloxacin intermediate, used in the synthesis process of chemical medicine. |
application | 4-hydroxypiperidine is a heterocyclic organic substance, which can be used as essence and fragrance, and can be used in laboratory research and development process and chemical and pharmaceutical production process. 4-hydroxypiperidine is a heterocyclic organic substance, which can be used as a fragrance. |