4-METHOXY-3-NITROPHENYLBORONIC ACID, PINACOL ESTER

4-METHOXY-3-NITROPHENYLBORONIC ACID, PINACOL ESTER - Names and Identifiers

Name	2-(4-methoxy-3-nitrophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
Synonyms	4-METHOXY-3-NITROPHENYLBORONIC ACID, PINACOL ESTER 2-(4-methoxy-3-nitrophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 2-(4-Methoxy-3-nitrophenyl)-4,4,5,5-tetraMethyl-1,3,2-dioxaborolane 1,3,2-Dioxaborolane, 2-(4-methoxy-3-nitrophenyl)-4,4,5,5-tetramethyl-
CAS	554411-20-0
InChI	InChI=1/C13H18BNO5/c1-12(2)13(3,4)20-14(19-12)9-6-7-11(18-5)10(8-9)15(16)17/h6-8H,1-5H3

4-METHOXY-3-NITROPHENYLBORONIC ACID, PINACOL ESTER - Physico-chemical Properties

Molecular Formula	C13H18BNO5
Molar Mass	279.1
Density	1.16g/cm³
Boling Point	393.7°C at 760 mmHg
Flash Point	191.9°C
Vapor Presure	4.75E-06mmHg at 25°C
Storage Condition	2-8°C
Refractive Index	1.513

4-METHOXY-3-NITROPHENYLBORONIC ACID, PINACOL ESTER - Risk and Safety

WGK Germany

4-METHOXY-3-NITROPHENYLBORONIC ACID, PINACOL ESTER - Introduction

2-(4-methoxy-3-nrophenyl)-4,4, 5,5-tetrathyl-1, 3,2-dioxaborolane is an organic compound with the chemical formula C14H19BNO5. Its nature is as follows:

1. Appearance: colorless crystalline solid;
2. melting point: about 110-112 ℃;
3. Boiling point: about 315-320 ℃;
4. Solubility: Soluble in polar organic solvents such as ethanol, dimethyl ether, slightly soluble in water.

The main uses of this compound include:

1. Reagent in organic synthesis: As a substitution reagent for aromatic hydrocarbons, it is commonly used to introduce methoxy and nitro groups in organic synthesis reactions;
2. drug research: because its structure contains benzene ring and nitro group, it can be used in drug research as a potential therapeutic substance;
3. Organic light-emitting diode (OLED) materials: can be used as OLED pigments and fluorescent dyes.

Regarding the preparation method, a commonly used synthesis method is to prepare 2-(4-methoxy-3-nitrophenyl)-4,4, 5,5-tetramethyyl-1, 3,2-dioxaborolane by co-thermal reaction of 2-methoxy-5-nitrophenylboronic acid and 1,3-epoxypentane.

When using and operating, you need to pay attention to the following safety information:

1. The compound is irritating and should avoid direct contact with skin and eyes;
2. in the operation need to take protective measures, such as wearing gloves, safety glasses, etc;
3. Avoid inhaling the dust or vapor of the compound, and maintain good ventilation during operation;
4. Avoid contact with strong oxidants and strong acids to avoid unsafe chemical reactions.

In summary, 2-(4-methoxy-3-nitrophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane is an organic compound with a wide range of application potential, but it is necessary to pay attention to safe operation when using it.

Last Update：2024-04-09 21:54:55