Molecular Formula | C8H9BrO |
Molar Mass | 201.06 |
Density | 1.379g/mLat 25°C(lit.) |
Melting Point | 240 °C |
Boling Point | 91°C1mm Hg(lit.) |
Flash Point | >230°F |
Vapor Presure | 0.0553mmHg at 25°C |
Refractive Index | n20/D 1.5780(lit.) |
Hazard Symbols | C - Corrosive |
Risk Codes | 34 - Causes burns |
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
UN IDs | UN 3265 8/PG 2 |
WGK Germany | 1 |
HS Code | 29093090 |
application | 4-methoxybenzyl bromide is an important pharmaceutical intermediate and has a wide range of applications in the pharmaceutical industry for the synthesis of tetrahydrobaltin (tetrahydropalmatine). |
Preparation | McCall et al. reacted with veratryl alcohol and hydrogen bromide in an ice bath in n-hexane and toluene to finally obtain 4-methoxybenzyl bromide, The yield is 68%, and this reaction produces by-products. |