4-Thiazolecarboxylic acid, 2-amino-, ethyl ester, monohydrobromide
4-Thiazolecarboxylic acid, 2-amino-, ethyl ester, monohydrobromide
CAS: 127942-30-7
Molecular Formula: C6H8N2O2S
4-Thiazolecarboxylic acid, 2-amino-, ethyl ester, monohydrobromide - Names and Identifiers
4-Thiazolecarboxylic acid, 2-amino-, ethyl ester, monohydrobromide - Physico-chemical Properties
| Molecular Formula | C6H8N2O2S |
| Molar Mass | 253.12 |
| Storage Condition | Sealed in dry,Room Temperature |
4-Thiazolecarboxylic acid, 2-amino-, ethyl ester, monohydrobromide - Introduction
Ethyl 2-amino-4-thiazolecarboxylate hydrobromic acid (abbreviated as ATAB) is an organic compound with the following properties and uses:
Nature:
-Appearance: White crystalline solid
-Molecular formula: C6H9BrN2O2S
-Molecular weight: 236.12g/mol
-Solubility: insoluble in water, soluble in organic solvents such as ethanol and acetone
Use:
- ATAB is commonly used in the preparation of other drugs or drug intermediates, such as acetyl azole, thiazoline and 4-hydroxy-2-aminothiazole.
-It can also be used as a meso agent in chiral synthesis.
Preparation Method:
- ATAB is mainly obtained by the esterification reaction of 4-fluoro-2-aminothiazole and glycolic acid.
-Specific reaction steps:
1. Esterification of 4-fluoro -2-aminothiazole under alkaline conditions to generate 4-fluoro -2-(ethyl acetate) thiazole.
2. react with hydrobromic acid under acidic conditions to generate 2-amino -4-thiazolecarboxylic acid ethyl ester hydrobromic acid.
Safety Information:
-The use and handling of ATABs should follow routine laboratory safety practices.
-It is a potentially toxic organic substance and should be avoided by inhalation, skin contamination and ingestion.
-Wear appropriate protective gloves, goggles and lab coats to ensure a fully ventilated work environment.
-If you come into contact with skin, rinse immediately with plenty of water. If you feel unwell, seek medical help.
-During storage and handling, keep ATABs away from ignition and oxidizing agents to avoid the risk of fire or explosion.
Nature:
-Appearance: White crystalline solid
-Molecular formula: C6H9BrN2O2S
-Molecular weight: 236.12g/mol
-Solubility: insoluble in water, soluble in organic solvents such as ethanol and acetone
Use:
- ATAB is commonly used in the preparation of other drugs or drug intermediates, such as acetyl azole, thiazoline and 4-hydroxy-2-aminothiazole.
-It can also be used as a meso agent in chiral synthesis.
Preparation Method:
- ATAB is mainly obtained by the esterification reaction of 4-fluoro-2-aminothiazole and glycolic acid.
-Specific reaction steps:
1. Esterification of 4-fluoro -2-aminothiazole under alkaline conditions to generate 4-fluoro -2-(ethyl acetate) thiazole.
2. react with hydrobromic acid under acidic conditions to generate 2-amino -4-thiazolecarboxylic acid ethyl ester hydrobromic acid.
Safety Information:
-The use and handling of ATABs should follow routine laboratory safety practices.
-It is a potentially toxic organic substance and should be avoided by inhalation, skin contamination and ingestion.
-Wear appropriate protective gloves, goggles and lab coats to ensure a fully ventilated work environment.
-If you come into contact with skin, rinse immediately with plenty of water. If you feel unwell, seek medical help.
-During storage and handling, keep ATABs away from ignition and oxidizing agents to avoid the risk of fire or explosion.
Last Update：2024-04-09 15:17:51
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Product Name: ETHYL 2-AMINOTHIAZOLE-4-CARBOXYLATE Visit Supplier Webpage Request for quotation
CAS: 127942-30-7
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Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
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CAS: 127942-30-7
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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