4-butyramidobenzoic acid
4-(Butyrylamino)benzoic acid
CAS: 99855-49-9
Molecular Formula: C11H13NO3
4-butyramidobenzoic acid - Names and Identifiers
4-butyramidobenzoic acid - Physico-chemical Properties
| Molecular Formula | C11H13NO3 |
| Molar Mass | 207.23 |
| Storage Condition | Room Temprature |
| Sensitive | IRRITANT |
| MDL | MFCD00448229 |
4-butyramidobenzoic acid - Risk and Safety
| Hazard Class | IRRITANT |
4-butyramidobenzoic acid - Introduction
4-(Butyrylamino)benzoic acid, chemical formula C13H15NO3, is an organic compound. Its properties are as follows:
1. Appearance: colorless crystal or solid
2. Melting point: 134-139°C
3. solubility: soluble in hot water, ethanol and dimethyl sulfoxide, slightly soluble in ether
4. chemical properties: under the condition of strong acid, it can be acidolysis to 4-amino benzoic acid and butyric acid.
5. Safety: At present, there are no clear toxicity data on this compound, but appropriate laboratory operations and protective measures should be paid attention.
4-(Butyrylamino) Purpose of benzoic acid:
1. The compound can be used as a pharmaceutical intermediate for the synthesis of antibiotics and other drugs; at the same time, it can also be used for the synthesis of other organic compounds.
2. As a dye and pigment intermediate, it has certain application potential.
Preparation Method:
A common preparation method is obtained by reacting p-aminobenzoic acid with butyryl chloride. First, under alkaline conditions, p-aminobenzoic acid reacts with sodium hydroxide to form p-aminobenzoic acid sodium salt. Then, 4-butyryl chloride was added to the reaction system to react to generate 4-(Butyrylamino)benzoic acid. The crystals were separated from the reaction solution to obtain the target product.
To sum up, 4-(Butyrylamino)benzoic acid is an organic compound commonly used in the synthesis of pharmaceutical intermediates and dye intermediates. Its preparation method is relatively simple, but it is necessary to pay attention to safety and protective measures in the experimental operation.
1. Appearance: colorless crystal or solid
2. Melting point: 134-139°C
3. solubility: soluble in hot water, ethanol and dimethyl sulfoxide, slightly soluble in ether
4. chemical properties: under the condition of strong acid, it can be acidolysis to 4-amino benzoic acid and butyric acid.
5. Safety: At present, there are no clear toxicity data on this compound, but appropriate laboratory operations and protective measures should be paid attention.
4-(Butyrylamino) Purpose of benzoic acid:
1. The compound can be used as a pharmaceutical intermediate for the synthesis of antibiotics and other drugs; at the same time, it can also be used for the synthesis of other organic compounds.
2. As a dye and pigment intermediate, it has certain application potential.
Preparation Method:
A common preparation method is obtained by reacting p-aminobenzoic acid with butyryl chloride. First, under alkaline conditions, p-aminobenzoic acid reacts with sodium hydroxide to form p-aminobenzoic acid sodium salt. Then, 4-butyryl chloride was added to the reaction system to react to generate 4-(Butyrylamino)benzoic acid. The crystals were separated from the reaction solution to obtain the target product.
To sum up, 4-(Butyrylamino)benzoic acid is an organic compound commonly used in the synthesis of pharmaceutical intermediates and dye intermediates. Its preparation method is relatively simple, but it is necessary to pay attention to safety and protective measures in the experimental operation.
Last Update：2024-04-09 21:01:54
