4-isoxazolecarboxylic acid, 5-amino-, ethyl ester

4-isoxazolecarboxylic acid, 5-amino-, ethyl ester - Names and Identifiers

Name	ethyl 5-amino-1,2-oxazole-4-carboxylate
Synonyms	TIMTEC-BB SBB010372 5-Amino-4-ethoxycarbonylisoxazole Ethyl 5-amino-isoxazolecarboxylate ETHYL 5-AMINOISOXAZOLE-4-CARBOXYLATE ethyl 5-amino-1,2-oxazole-4-carboxylate 4-Isoxazolecarboxylic acid, 5-aMino-, ethyl ester 4-isoxazolecarboxylic acid, 5-amino-, ethyl ester 4-Isoxazolecarboxylicacid,5-amino-,ethylester(6CI,9CI)
CAS	34859-64-8
InChI	InChI=1/C6H8N2O3/c1-2-10-6(9)4-3-8-11-5(4)7/h3H,2,7H2,1H3

4-isoxazolecarboxylic acid, 5-amino-, ethyl ester - Physico-chemical Properties

Molecular Formula	C6H8N2O3
Molar Mass	156.14
Density	1.278±0.06 g/cm3(Predicted)
Melting Point	70-75°C
Boling Point	288.3±20.0 °C(Predicted)
Flash Point	128.2°C
Vapor Presure	0.00235mmHg at 25°C
pKa	-2.49±0.10(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2–8 °C
Refractive Index	1.522
MDL	MFCD00014093

4-isoxazolecarboxylic acid, 5-amino-, ethyl ester - Risk and Safety

Safety Description	24/25 - Avoid contact with skin and eyes.
WGK Germany	3
HS Code	29349990
Hazard Class	IRRITANT

4-isoxazolecarboxylic acid, 5-amino-, ethyl ester - Introduction

Ethyl 5-amino-1,2-oxazole-4-carboxylate is an organic compound with the formula C6H8N2O3.

Nature:
ethyl 5-amino-1,2-oxazole-4-carboxylate is a white crystalline solid with a faint characteristic ammonia odor. It is soluble in alcohols and organic solvents, but hardly soluble in water.

Use:
ethyl 5-amino-1,2-oxazole-4-carboxylate is widely used in the field of medicine as a synthetic drug intermediate. It can be used to synthesize anticancer drugs, antidepressant drugs, etc. In addition, it can also be used as a ligand derivative and a ligand crosslinking agent.

Preparation Method:
Ethyl 5-amino-1,2-oxazole-4-carboxylate has many preparation methods. One of the commonly used methods is through isoxazole-5-formaldehyde and ethanolamine in the presence of sodium carbonate Condensation reaction.

Safety Information:
ethyl 5-amino-1,2-oxazole-4-carboxylate is a chemical substance that must be used in accordance with safe operating procedures. It may cause irritation and injury when in contact with the skin, eyes or inhalation, so direct contact should be avoided. Wear appropriate protective gloves, goggles and protective clothing when using. During storage and handling, keep away from fire and heat sources, and avoid contact with oxidants and strong acids. Seek immediate medical attention if accidentally exposed or swallowed.

Last Update：2024-04-09 20:52:54