4-methoxypyridine-3-boronic acid

4-methoxypyridine-3-boronic acid - Names and Identifiers

Name	Boronic acid, (4-methoxy-3-pyridinyl)-
Synonyms	AKOS BRN-0192 AKOS BBS-00001323 4-methoxypyridine-3-boronic acid 4-METHOXYPYRIDINE-3-BORONIC ACID 4-METHOXY-3-PYRIDINEBORONIC ACID 4-Methoxy-3-pyridineboronic acid 4-METHOXY-3-PYRIDINYLBORONIC ACID (4-methoxypyridin-3-yl)boronic acid (4-METHOXYPYRIDIN-3-YL)BORONIC ACID (4-Methoxy-3-pyridinyl)-boronic acid Boronic acid, (4-methoxy-3-pyridinyl)- 4-METHOXYPYRIDINE-3-BORONIC ACID HYDRATE
CAS	355004-67-0
InChI	InChI=1/C6H8BNO3/c1-11-6-2-3-8-4-5(6)7(9)10/h2-4,9-10H,1H3

4-methoxypyridine-3-boronic acid - Physico-chemical Properties

Molecular Formula	C6H8BNO3
Molar Mass	152.94
Density	1.24±0.1 g/cm3(Predicted)
Boling Point	357.0±52.0 °C(Predicted)
Flash Point	169.7°C
Vapor Presure	1.03E-05mmHg at 25°C
Appearance	Powder
Color	Cream
pKa	4.03±0.58(Predicted)
Storage Condition	Refrigerator (+4°C)
Refractive Index	1.523

4-methoxypyridine-3-boronic acid - Risk and Safety

Risk Codes	R36/37/38 - Irritating to eyes, respiratory system and skin. R22 - Harmful if swallowed
Safety Description	S37/39 - Wear suitable gloves and eye/face protection S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Hazard Note	Irritant

4-methoxypyridine-3-boronic acid - Introduction

Boronic acid, (4-methoxy-3-pyridinyl)-is an organic compound with the chemical formula C6H8BNO3. It is a white solid, soluble in water and organic solvents, and stable at room temperature. Its molecular structure contains a boronic acid group and a 4-methoxypyridine group.

Boronic acid, (4-methoxy-3-pyridinyl)-has a wide range of applications in the field of organic synthesis. It is an important boronic acid reagent, which can be used as a ligand in metal-catalyzed reactions, and participate in Suzuki-Miyaura cross-coupling reactions, Heck reactions, acetylene-ethylene-azide reactions, etc. In addition, it can also be used for the construction of heterocyclic compounds, the preparation of fluorescent probes and the design of active molecules in the field of medicine.

The method of preparing Boronic acid, (4-methoxy-3-pyridinyl)-A common method is to react boric acid and 4-methoxypyridine. The specific steps include dissolving 4-methoxypyridine in absolute ethanol, then adding boric acid to the solution for reaction, producing Boronic acid, (4-methoxy-3-pyridinyl)-salt, and finally obtaining the target product by acid hydrolysis.

Regarding safety information, Boronic acid, (4-methoxy-3-pyridinyl)-belongs to chemicals, and protective measures should be paid attention to when using. It may be irritating to the eyes, skin and respiratory tract, so wear appropriate protective gloves, glasses and a mask when used. At the same time, it is necessary to operate in a well-ventilated environment to avoid inhaling gas or dust. If exposed or inhaled, rinse immediately with water and seek medical help.

Last Update：2024-04-09 21:11:58