4-phenyl(phthalene-1-yl)boronic acid
4-phenyl-1-naphthalene boronic acid
CAS: 16241-07-5
Molecular Formula: C16H13BO2
4-phenyl(phthalene-1-yl)boronic acid - Names and Identifiers
4-phenyl(phthalene-1-yl)boronic acid - Physico-chemical Properties
| Molecular Formula | C16H13BO2 |
| Molar Mass | 248.08422 |
4-phenyl(phthalene-1-yl)boronic acid - Introduction
4-phenyl-1-naphthalene boronic acid is an organic compound with the chemical formula ccrisis bno₂. Its main properties are as follows:
1. Appearance: White crystalline solid.
2. Solubility: Soluble in organic solvents, such as dimethyl sulfoxide, ethanol and Ether solvents.
3. Melting Point: about 172-176 ℃.
4-phenyl-1-napthalene boronic acid has a wide range of uses in organic synthesis:
1. Reagent: It can be used as a coupling reagent in organic synthesis, for example, cross-coupling reaction with aryl halide in Suzuki reaction to generate aromatic hydrocarbon compounds.
2. Photosensitive material: because it contains naphthalene groups, it can be used for the synthesis of photosensitive materials, such as photosensitive paper, photosensitive film, etc.
3. Fluorescent probe: It has a fluorescent probe effect on certain metal ions and can be used in the fields of analytical chemistry and biomedicine.
The preparation methods of 4-phenyl-1-napthalene boronic acid mainly include the following:
1. Through organic synthesis reaction: A commonly used method is to generate 4-phenyl-1-napthalene boronic acid by esterification with 1-naphthol.
2. Through the reaction of boric acid with the corresponding brominated aromatic hydrocarbon: brominated aromatic hydrocarbon is generated, and then reacted with boric acid to obtain 4-phenyl-1-napthalene boronic acid.
Regarding safety information, 4-phenyl-1-napthalene boronic acid is an organic compound, and the following safety precautions should be noted:
1. Avoid inhalation and contact with skin: Operation should wear protective gloves and respiratory protective equipment, avoid direct contact with skin and inhalation of gas or dust.
2. Storage and handling: should be stored in a dry, ventilated place, away from fire and oxidant. Avoid contact with strong oxidants and strong acids.
3. Waste disposal: in accordance with local laws and regulations to avoid environmental pollution.
When using these chemicals, please always follow the laboratory's safe operating procedures and consult a chemical expert according to the specific situation.
1. Appearance: White crystalline solid.
2. Solubility: Soluble in organic solvents, such as dimethyl sulfoxide, ethanol and Ether solvents.
3. Melting Point: about 172-176 ℃.
4-phenyl-1-napthalene boronic acid has a wide range of uses in organic synthesis:
1. Reagent: It can be used as a coupling reagent in organic synthesis, for example, cross-coupling reaction with aryl halide in Suzuki reaction to generate aromatic hydrocarbon compounds.
2. Photosensitive material: because it contains naphthalene groups, it can be used for the synthesis of photosensitive materials, such as photosensitive paper, photosensitive film, etc.
3. Fluorescent probe: It has a fluorescent probe effect on certain metal ions and can be used in the fields of analytical chemistry and biomedicine.
The preparation methods of 4-phenyl-1-napthalene boronic acid mainly include the following:
1. Through organic synthesis reaction: A commonly used method is to generate 4-phenyl-1-napthalene boronic acid by esterification with 1-naphthol.
2. Through the reaction of boric acid with the corresponding brominated aromatic hydrocarbon: brominated aromatic hydrocarbon is generated, and then reacted with boric acid to obtain 4-phenyl-1-napthalene boronic acid.
Regarding safety information, 4-phenyl-1-napthalene boronic acid is an organic compound, and the following safety precautions should be noted:
1. Avoid inhalation and contact with skin: Operation should wear protective gloves and respiratory protective equipment, avoid direct contact with skin and inhalation of gas or dust.
2. Storage and handling: should be stored in a dry, ventilated place, away from fire and oxidant. Avoid contact with strong oxidants and strong acids.
3. Waste disposal: in accordance with local laws and regulations to avoid environmental pollution.
When using these chemicals, please always follow the laboratory's safe operating procedures and consult a chemical expert according to the specific situation.
Last Update：2024-04-10 22:29:15
