400652-48-4

400652-48-4 - Names and Identifiers

Name	[(R)-1-(Aminomethyl)-2-phenylethyl]-carbamic acid benzyl ester
Synonyms	(R)-N-Cbz-1-(aminomethyl)-2-phenylethylamine (R)-benzyl 1-amino-3-phenylpropan-2-ylcarbamate benzyl (R)-(1-amino-3-phenylpropan-2-yl)carbamate [(R)-1-(Aminomethyl)-2-phenylethyl]-carbamic acid benzyl ester [(R)-1-(AMinoMethyl)-2-phenylethyl]-carbaMic acid benzyl ester [(1R)-1-(AMINOMETHYL)-2-PHENYLETHYL]-CARBAMIC ACID PHENYLMETHYL ESTER Carbamic acid, N-[(1R)-1-(aminomethyl)-2-phenylethyl]-, phenylmethyl ester
CAS	400652-48-4

400652-48-4 - Physico-chemical Properties

Molecular Formula	C17H20N2O2
Molar Mass	284.35
Storage Condition	under inert gas (nitrogen or Argon) at 2–8 °C

400652-48-4 - Introduction

[(R)-1-(Aminomethyl)-2-phenylethyl]-carbamic acid ester is an organic compound whose chemical formula is C16H19NO2.

Nature:
-Appearance: It is a white or off-white crystalline powder.
-Solubility: It can be dissolved in some organic solvents, such as chloroform, dichloromethane and methanol, but is almost insoluble in water.
-Melting point: Its melting point is about 100-103°C.

Use:
- [(R)-1-(Aminomethyl)-2-phenylethyl]-carbamic acid benzyl ester is a part of the chiral skeleton and is often used as a raw material for chiral intermediates or chiral catalysts.
-It can be used for asymmetric catalytic reactions in organic synthesis reactions, and can effectively catalyze amide synthesis and aryl ethanol synthesis reactions.
-In addition, it can also be used to produce organic compounds such as medicines and pesticides.

Preparation Method:
[(R)-1-(Aminomethyl)-2-phenylethyl]-carbamic acid benzyl ester is mainly prepared by organic synthesis.
-A common preparation method is to react methyl p-toluenesulfonate and N-benzyl-N-methylethylenediamine under base catalysis.
-The intermediates generated during the reaction undergo reasonable subsequent operations and purification steps to obtain [(R)-1-(Aminomethyl)-2-phenylethyl]-carbamic acid benzyl ester.

Safety Information:
[(R)-1-(Aminomethyl)-2-phenylethyl]-carbamic the following safety precautions for laboratory use of acid benzyl ester:
-Because it is an organic substance, it needs to be prevented from contacting the skin and eyes.
-use to maintain good ventilation conditions, avoid inhalation of its dust or steam.
-Avoid contact with oxidants and strong acids during storage.
-When using or handling this compound, follow relevant safety procedures and wear appropriate protective equipment.

Last Update：2024-04-09 21:04:16