450-83-9

450-83-9 - Names and Identifiers

Name	2-Methoxy-4-Fluorobenzaldehyde
Synonyms	4-Fluoro-o-anisaldehyde Fluoromethoxybenzaldehyde4 4-Fluoro-2-methoxybenzaldehyde 4-FLUORO-2-METHOXYBENZALDEHYDE 2-Methoxy-4-Fluorobenzaldehyde 2-METHOXY-4-FLUOROBENZALDEHYDE 5-Fluoro-2-formylanisole, 4-Fluoro-o-anisaldehyde 5-Fluoro-2-formylanisole, 5-Fluoro-2-formylphenyl methyl ether
CAS	450-83-9
EINECS	200-258-5
InChI	InChI=1/C8H7FO2/c1-11-8-4-7(9)3-2-6(8)5-10/h2-5H,1H3

450-83-9 - Physico-chemical Properties

Molecular Formula	C8H7FO2
Molar Mass	154.14
Density	1.192±0.06 g/cm3(Predicted)
Melting Point	55 °C
Boling Point	224.6±20.0 °C(Predicted)
Flash Point	87.2°C
Solubility	soluble in Methanol
Vapor Presure	0.0905mmHg at 25°C
Appearance	Crystalline powder
Color	White to Orange to Green
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Sensitive	Air Sensitive
Refractive Index	1.525
MDL	MFCD00143318

450-83-9 - Risk and Safety

Risk Codes	R36/37/38 - Irritating to eyes, respiratory system and skin. R52 - Harmful to aquatic organisms R41 - Risk of serious damage to eyes R37/38 - Irritating to respiratory system and skin. R22 - Harmful if swallowed
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S39 - Wear eye / face protection.
HS Code	29124990
Hazard Note	Irritant

450-83-9 - Introduction

It is an organic compound with the chemical formula C8H7FO2. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: Colorless or light yellow crystal
-Melting point: 44-48 degrees Celsius
-Sedimentation: 1.325g/cm3
-Solubility: Soluble in organic solvents such as ethanol and dichloromethane

Use:
-is one of the commonly used intermediates in organic synthesis. It is possible to synthesize various organic compounds by converting its side chain or reacting in its acidic environment.
-In drug synthesis, it is often used to prepare highly effective selective drugs, such as antibacterial agents, anti-tumor agents and anti-inflammatory agents.

Preparation Method: The preparation of
-fluoridation is usually achieved by fluorination reaction of 2-fluoro-4-methoxybenzaldehyde. Specific methods include addition of a fluorination reagent and a heating reaction, or use of an electrochemical fluorination method, etc.

Safety Information:
-may be harmful to the human body, and may cause irritation to the eyes, respiratory system and skin.
-Wear appropriate protective equipment such as chemical goggles, gloves and respiratory protection when used or handled.
-Avoid breathing gas, vapor, spray or dust, and keep the work area well ventilated.
-It is recommended to store in a safe storage cabinet and keep it away from flammable substances and oxidants.

Please note that when using or handling any chemical, you should follow the relevant safety procedures in your area and seek professional guidance when necessary.

Last Update：2024-04-09 15:17:57