Name | (+)-Sophoranol |
Synonyms | Sophoranol (+)-Sophoranol 5-Hydroxymatrine 5α-Hydroxymatridin-15-one 5-Hydroxymatridine-15-one |
CAS | 3411-37-8 |
Molecular Formula | C15H24N2O2 |
Molar Mass | 264.36 |
Density | 1.25 |
Melting Point | 169-170℃ |
Boling Point | 437.6±45.0 °C(Predicted) |
Appearance | Cryst. |
pKa | 14.05±0.20(Predicted) |
Storage Condition | 2-8℃ |
In vitro study | Sophoranol has a remarkable inhibitory effect on the secretion of HBsAg and HBeAg n in the 2.2.15 cell line. |
biological activity | sloranol is an alkaloid that can be isolated from S. flavescens and has antiviral activity. Sloranol has anti-hepatitis B Virus (HBV) activity. Respiratory Syncytial Virus (RSV) has a strong antiviral activity, and its IC50 value is 10.4g/mL. |
Target | IC50: 10.4 μg/mL (RSV) |