5'-Tosyladenosine
5'-Tosyladenosine
CAS: 5135-30-8
Molecular Formula: C17H19N5O6S
5'-Tosyladenosine - Names and Identifiers
| Name | 5'-Tosyladenosine |
| Synonyms | 5'-Tosyladenosine 5'-TOSYLADENOSINE adenosine 5'-tosylate Tolysulfonyl adenosine p-Toluenesulfonyl adenosine 5'-O-(P-TOLUENESULFONYL)-ADENOSINE 5'-O-(p-Toluenesulfonyl)-D-adenosine 5'-O-[(4-methylphenyl)sulfonyl]adenosine (3xi)-5'-O-[(4-methylphenyl)sulfonyl]adenosine N~8~-[5-(diethylamino)pentan-2-yl]-3-(3,4,5-trimethoxyphenyl)pyrido[2,3-b]pyrazine-6,8-diamine |
| CAS | 5135-30-8 |
| EINECS | 225-883-1 |
| InChI | InChI=1/C17H19N5O6S/c1-9-2-4-10(5-3-9)29(25,26)27-6-11-13(23)14(24)17(28-11)22-8-21-12-15(18)19-7-20-16(12)22/h2-5,7-8,11,13-14,17,23-24H,6H2,1H3,(H2,18,19,20)/t11-,13+,14?,17-/m1/s1 |
5'-Tosyladenosine - Physico-chemical Properties
| Molecular Formula | C17H19N5O6S |
| Molar Mass | 421.43 |
| Density | 1.3663 (rough estimate) |
| Melting Point | 151 °C |
| Boling Point | 760.1±70.0 °C(Predicted) |
| Solubility | DMSO (Slightly), Methanol (Slightly, Heated) |
| Appearance | Solid |
| Color | White to Off-White |
| pKa | 12.97±0.70(Predicted) |
| Storage Condition | Keep in dark place,Inert atmosphere,2-8°C |
| Refractive Index | 1.6460 (estimate) |
| MDL | MFCD00005751 |
| Physical and Chemical Properties | Melting Point 151-153°C |
5'-Tosyladenosine - Risk and Safety
| Safety Description | 24/25 - Avoid contact with skin and eyes. |
| HS Code | 29349990 |
5'-Tosyladenosine - Introduction
5 '-Tosyladenosine(5'-Tosyladenosine) is an organic compound whose chemical formula is C20H23N5O7S and whose molecular structure has a tosylate group attached to the 5 '-position of adenosine.
5 '-Tosyladenosine is commonly used as a reagent in biochemical research for the synthesis of nucleic acids and nucleic acid drugs. It also has important applications in medicinal chemistry, especially in the development of antiviral and anticancer drugs.
The 5 '-Tosyladenosine can be prepared by first introducing a protecting group (p-toluenesulfonyl group is generally selected) at the 5'-position from adenosine, then carrying out a reaction to link the protecting group to adenosine, and finally removing the protecting group to obtain the target product.
Regarding safety information, 5 '-Tosyladenosine is an organic compound and has certain toxicity. Appropriate safety precautions, such as wearing protective gloves, goggles and protective clothing, should be taken when using or handling the substance. Avoid direct contact with skin and eyes, and avoid inhalation or ingestion. If accidental contact causes discomfort or paresthesia, seek medical attention immediately.
5 '-Tosyladenosine is commonly used as a reagent in biochemical research for the synthesis of nucleic acids and nucleic acid drugs. It also has important applications in medicinal chemistry, especially in the development of antiviral and anticancer drugs.
The 5 '-Tosyladenosine can be prepared by first introducing a protecting group (p-toluenesulfonyl group is generally selected) at the 5'-position from adenosine, then carrying out a reaction to link the protecting group to adenosine, and finally removing the protecting group to obtain the target product.
Regarding safety information, 5 '-Tosyladenosine is an organic compound and has certain toxicity. Appropriate safety precautions, such as wearing protective gloves, goggles and protective clothing, should be taken when using or handling the substance. Avoid direct contact with skin and eyes, and avoid inhalation or ingestion. If accidental contact causes discomfort or paresthesia, seek medical attention immediately.
Last Update：2024-04-09 20:02:46
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