5,6,7,7a-Tetrahydro-4,4,7aα-trimethyl-6α-hydroxybenzofuran-2(4H)-one - Names and Identifiers
Name | Loliolid
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Synonyms | Loliolid Caulilide loliolide NSC 289632 Digiprolactone 5,6,7,7a-Tetrahydro-6α-hydroxy-4,4,7aα-trimethylbenzofuran-2(4H)-one 5,6,7,7a-Tetrahydro-4,4,7aα-trimethyl-6α-hydroxybenzofuran-2(4H)-one 2(4H)-Benzofuranone,5,6,7,7a-tetrahydro-6-hydroxy-4,4,7a-trimethyl-, (6S,7aR)-
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CAS | 5989-02-6
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5,6,7,7a-Tetrahydro-4,4,7aα-trimethyl-6α-hydroxybenzofuran-2(4H)-one - Physico-chemical Properties
Molecular Formula | C11H16O3
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Molar Mass | 196.24 |
Density | 1.16±0.1 g/cm3(Predicted) |
Melting Point | 151-153℃ |
Boling Point | 352.7±42.0 °C(Predicted) |
Appearance | Powder |
pKa | 14.39±0.60(Predicted) |
Storage Condition | 2-8℃ |
5,6,7,7a-Tetrahydro-4,4,7aα-trimethyl-6α-hydroxybenzofuran-2(4H)-one - Introduction
Loliolid(Loliolid) is an organic compound with the chemical formula C12H14O3. It is a white to light yellow crystalline solid, soluble in a variety of organic solvents, such as ethanol and dichloromethane.
Loliolid has a wide range of uses in medicinal chemistry. It is widely used as a pharmaceutical intermediate, especially in the synthesis of antibacterial and anti-inflammatory drugs. In addition, Loliolid is also used in the synthesis of pesticides and other chemicals.
The method of preparing Loliolid can be achieved by acid-catalyzed reaction of cryptic acid ester and aromatic aldehyde in an organic solvent.
Pay attention to relevant safety information when using Loliolid. It is toxic and may be harmful to humans. Necessary protective measures should be taken during operation, including wearing appropriate protective gloves, glasses and respirators. At the same time, ensure that the operation is well ventilated and avoid inhalation of its vapors or contact with skin. In case of accidental contact or ingestion, seek medical attention immediately.
Last Update:2024-04-09 20:52:54