5,6-DICHLOROPYRIDIN-3-YL-BORONIC ACID

5,6-DICHLOROPYRIDIN-3-YL-BORONIC ACID - Names and Identifiers

Name	2,3-Dichloropyridine-5-boronic Acid
Synonyms	2,3-Dichloropyridine-5-boronic 2,3-Dichloropyridine-5-boronicaci 2,3-DICHLOROPYRIDINE-5-BORONIC ACID 5,6-Dichloropyridine-3-boronic acid 2,3-Dichloropyridine-5-boronic Acid 5,6-DICHLOROPYRIDIN-3-YL-BORONIC ACID Boronic acid, B-(5,6-dichloro-3-pyridinyl)-
CAS	1072944-15-0

5,6-DICHLOROPYRIDIN-3-YL-BORONIC ACID - Physico-chemical Properties

Molecular Formula	C5H4BCl2NO2
Molar Mass	191.81
Density	1.56±0.1 g/cm3(Predicted)
Melting Point	>160°C (dec.)
Boling Point	364.1±52.0 °C(Predicted)
Solubility	DMSO (Slightly), Methanol (Slightly, Heated)
Appearance	Solid
Color	Pale Brown to Light Orange
pKa	5.70±0.11(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C

5,6-DICHLOROPYRIDIN-3-YL-BORONIC ACID - Introduction

3,3-Dichloropyridine-5-boronic acid (2, acid) is an organic compound with the formula C5H4BCl2NO2. The following is a description of its nature, use, preparation and safety information:

Nature:
-2,3-dichloropyridine -5-boronic acid is a solid crystal, which is a white to light yellow crystalline powder at room temperature.
-It can be dissolved in many organic solvents, such as chlorinated hydrocarbons, alcohols and ethers.
-Its melting point is about 118-121°C, and it can decompose during heating.
- 2,3-dichloropyridine -5-boric acid is an organic boron compound with good chemical stability.

Use:
-2,3-dichloropyridine -5-boronic acid is often used as an important intermediate in organic synthesis. It can participate in the Suzuki coupling reaction and other important organic synthesis reactions, synthesis of other organic compounds, such as organic electronic materials, drug molecules and catalysts.
-Because of its good reactivity and selectivity, it is widely used in organic synthesis.

Preparation Method:
-2,3-dichloropyridine-5-boronic acid is usually produced by reacting 2,3-dichloropyridine with triphenylphosphine-boronic acid or the like.
-The reaction is usually carried out under an inert atmosphere, such as a nitrogen atmosphere, and is assisted by a solvent.

Safety Information:
-2,3-dichloropyridine -5-boric acid has certain toxicity and irritation, and direct contact with skin, eyes and respiratory tract should be avoided.
-Wear appropriate personal protective equipment such as lab gloves, goggles and protective masks during use.
-When storing and handling, it should be kept in a tight container, away from fire and heat sources, and avoid contact with oxidants, strong acids and other substances.
-When using and handling 2,3-dichloropyridine -5-boric acid, please strictly follow the relevant safety procedures and operating instructions. In the event of an accident, appropriate first aid measures should be taken immediately and medical assistance should be obtained in a timely manner.

Last Update：2024-04-09 21:04:16