5-(Benzyloxy)-6-bromo-2-pyridinecarbaldehyde
5-(Benzyloxy)-6-bromo-2-pyridinecarbaldehyde
CAS: 1192263-80-1
Molecular Formula: C13H10BrNO2
5-(Benzyloxy)-6-bromo-2-pyridinecarbaldehyde - Names and Identifiers
5-(Benzyloxy)-6-bromo-2-pyridinecarbaldehyde - Physico-chemical Properties
| Molecular Formula | C13H10BrNO2 |
| Molar Mass | 292.13 |
| Density | 1.496±0.06 g/cm3(Predicted) |
| Melting Point | 109～111℃ |
| Boling Point | 416.0±40.0 °C(Predicted) |
| pKa | 0.45±0.10(Predicted) |
| Storage Condition | 2-8°C |
| Sensitive | IRRITANT |
| MDL | MFCD13193072 |
5-(Benzyloxy)-6-bromo-2-pyridinecarbaldehyde - Introduction
5-(Benzyloxy)-is an organic compound whose chemical formula is C12H9BrNO2.
Nature:
-Appearance: It is a white to yellow solid.
-Solubility: It is soluble in many organic solvents, such as ethanol, dimethyl sulfoxide and toluene.
Use:
-As an organic synthesis intermediate: It can be used as an intermediate for the synthesis of other organic compounds, such as drugs, pesticides and functional materials.
-Heterocyclic synthesis: It can be used to synthesize compounds with heterocyclic structures.
Preparation Method:
5-(Benzyloxy)-It can be prepared by the following steps:
1.2-benzyl -2-acetol was obtained by acid-catalyzed condensation of benzyl alcohol and acetone
2. react 2-benzyl -2-acetone alcohol with bromoacetic acid to obtain 5-(benzyloxy)-6-bromopyridinol
3. Finally, 5-(benzyloxy)-6-bromopyridinol is converted into 5-(Benzyloxy)-5-pyridyl by acid-catalyzed dehydration reaction.
Safety Information:
-It may irritate the eyes, skin and respiratory tract, so you should wear protective equipment and avoid contact during operation.
-During storage and handling, care should be taken to avoid contact with oxidants, acids and alkalis.
-It should be operated in a well-ventilated place to avoid inhalation of vapor.
-Follow proper laboratory procedures when using chemicals and understand the risks and safety measures.
Nature:
-Appearance: It is a white to yellow solid.
-Solubility: It is soluble in many organic solvents, such as ethanol, dimethyl sulfoxide and toluene.
Use:
-As an organic synthesis intermediate: It can be used as an intermediate for the synthesis of other organic compounds, such as drugs, pesticides and functional materials.
-Heterocyclic synthesis: It can be used to synthesize compounds with heterocyclic structures.
Preparation Method:
5-(Benzyloxy)-It can be prepared by the following steps:
1.2-benzyl -2-acetol was obtained by acid-catalyzed condensation of benzyl alcohol and acetone
2. react 2-benzyl -2-acetone alcohol with bromoacetic acid to obtain 5-(benzyloxy)-6-bromopyridinol
3. Finally, 5-(benzyloxy)-6-bromopyridinol is converted into 5-(Benzyloxy)-5-pyridyl by acid-catalyzed dehydration reaction.
Safety Information:
-It may irritate the eyes, skin and respiratory tract, so you should wear protective equipment and avoid contact during operation.
-During storage and handling, care should be taken to avoid contact with oxidants, acids and alkalis.
-It should be operated in a well-ventilated place to avoid inhalation of vapor.
-Follow proper laboratory procedures when using chemicals and understand the risks and safety measures.
Last Update：2024-04-09 20:49:11
