5-(hydroxymethyl) pyridin-2(1H)-one
5-(hydroxymethyl) pyridin-2(1H)-one
CAS: 109205-68-7
Molecular Formula: C6H7NO2
5-(hydroxymethyl) pyridin-2(1H)-one - Names and Identifiers
5-(hydroxymethyl) pyridin-2(1H)-one - Physico-chemical Properties
| Molecular Formula | C6H7NO2 |
| Molar Mass | 125.13 |
| Density | 1.225±0.06 g/cm3(Predicted) |
| Boling Point | 428.0±27.0 °C(Predicted) |
| Flash Point | 212.7°C |
| Vapor Presure | 4.03E-09mmHg at 25°C |
| pKa | 11.56±0.10(Predicted) |
| Storage Condition | Sealed in dry,Room Temperature |
| Refractive Index | 1.538 |
5-(hydroxymethyl) pyridin-2(1H)-one - Introduction
2-hydroxy-5-hydroxymethylpyridine (pyridine) is an organic compound with the chemical formula C6H7NO2.
Nature:
-Appearance: 2-Hydroxy-5-hydroxymethylpyridine is a colorless or pale yellow liquid.
-Solubility: Soluble in water and alcohol solvents.
-Melting point and boiling point: the melting point is 14-18 degrees Celsius, and the boiling point is 196-197 degrees Celsius.
Use:
-2-Hydroxy-5-hydroxymethylpyridine is widely used as a reagent in organic synthesis. It can be used as a catalyst for esterification reactions, catalyzing the reaction of alcohols with acids to form esters.
-The compound can also be used to prepare pharmaceutical intermediates and pharmaceuticals.
Preparation Method:
-2-Hydroxy-5-hydroxymethylpyridine can be prepared by a Kotropos-type condensation reaction of 2-hydroxy-5-hydroxymethylpyridine aldehyde (aldehyde). The reaction needs to use sodium cyanide or hydrogen cyanide to treat 1-methyl -2-pyridine formaldehyde, generate 2-hydroxyl -5-methyl pyridine alcohol aldehyde, and then through catalytic hydrogenation reaction to obtain 2-hydroxyl -5-hydroxymethyl pyridine.
Safety Information:
-2-hydroxy-5-hydroxymethylpyridine has low toxicity, but it is still necessary to avoid inhalation or contact with skin, eyes and other parts.
-During use, good ventilation should be taken and appropriate personal protective equipment should be worn, such as chemical protective glasses and gloves.
-Store in an airtight container, away from ignition and oxidizing agents.
Nature:
-Appearance: 2-Hydroxy-5-hydroxymethylpyridine is a colorless or pale yellow liquid.
-Solubility: Soluble in water and alcohol solvents.
-Melting point and boiling point: the melting point is 14-18 degrees Celsius, and the boiling point is 196-197 degrees Celsius.
Use:
-2-Hydroxy-5-hydroxymethylpyridine is widely used as a reagent in organic synthesis. It can be used as a catalyst for esterification reactions, catalyzing the reaction of alcohols with acids to form esters.
-The compound can also be used to prepare pharmaceutical intermediates and pharmaceuticals.
Preparation Method:
-2-Hydroxy-5-hydroxymethylpyridine can be prepared by a Kotropos-type condensation reaction of 2-hydroxy-5-hydroxymethylpyridine aldehyde (aldehyde). The reaction needs to use sodium cyanide or hydrogen cyanide to treat 1-methyl -2-pyridine formaldehyde, generate 2-hydroxyl -5-methyl pyridine alcohol aldehyde, and then through catalytic hydrogenation reaction to obtain 2-hydroxyl -5-hydroxymethyl pyridine.
Safety Information:
-2-hydroxy-5-hydroxymethylpyridine has low toxicity, but it is still necessary to avoid inhalation or contact with skin, eyes and other parts.
-During use, good ventilation should be taken and appropriate personal protective equipment should be worn, such as chemical protective glasses and gloves.
-Store in an airtight container, away from ignition and oxidizing agents.
Last Update：2024-04-09 02:00:41
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View History
5-(hydroxymethyl) pyridin-2(1H)-one
30753-39-0
25452-22-6
4H-Pyrido(1,2-a)pyrimidine-3-carboxylic acid, 1,6,7,8,9,9a-hexahydro-1 ,6-dimethyl-4-oxo-, ethyl ester
1,3-bis(2-Methoxypyridin-3-yl)urea
cocainechloride
benzenepropanoic acid, beta-(benzoylamino)-alpha-hydroxy-, (alphaR,betaS)-
1261909-92-5
N-Propylthiophene-3-carboxamide
H-VAL-GLY-NH2 · HCL
30753-39-0
25452-22-6
4H-Pyrido(1,2-a)pyrimidine-3-carboxylic acid, 1,6,7,8,9,9a-hexahydro-1 ,6-dimethyl-4-oxo-, ethyl ester
1,3-bis(2-Methoxypyridin-3-yl)urea
cocainechloride
benzenepropanoic acid, beta-(benzoylamino)-alpha-hydroxy-, (alphaR,betaS)-
1261909-92-5
N-Propylthiophene-3-carboxamide
H-VAL-GLY-NH2 · HCL