5-(hydroxymethyl)furan-2-carboxylic acid

5-(hydroxymethyl)furan-2-carboxylic acid - Names and Identifiers

Name	5-(hydroxymethyl)furan-2-carboxylic acid
Synonyms	65-I Nsc 40739 Sumiki's acid RARECHEM AL BD 0265 5-hydroxymethyl-2-furoic acid 5-(Hydroxymethyl)-2-furoic acid 2-Furoic acid, 5-(hydroxymethyl)- (8ci) 5-Hydroxymethyl-Furan-2-Carboxylic Acid 5-(hydroxymethyl)furan-2-carboxylic acid 2-Furancarboxylic acid,5-(hydroxymethyl)- 2-Furancarboxylic acid, 5-(hydroxymethyl)- 2-Furancarboxylic acid, 5-(hydroxymethyl)- (9ci)
CAS	6338-41-6
InChI	InChI=1/C6H6O4/c7-3-4-1-2-5(10-4)6(8)9/h1-2,7H,3H2,(H,8,9)

5-(hydroxymethyl)furan-2-carboxylic acid - Physico-chemical Properties

Molecular Formula	C6H6O4
Molar Mass	142.11
Density	1.441±0.06 g/cm3(Predicted)
Melting Point	247°C (dec.)
Boling Point	349.4±32.0 °C(Predicted)
Flash Point	165.1°C
Solubility	DMSO (Slightly), Methanol (Slightly)
Vapor Presure	1.77E-05mmHg at 25°C
Appearance	Solid
Color	White to Light Beige
pKa	3.11±0.10(Predicted)
Storage Condition	-20°C
Stability	Light Sensitive, Very Hygroscopic
Refractive Index	1.561
In vitro study	5-Hydroxymethyl-2-furancarboxylic acid (HMFA)can be used as a biomarker for the exposure to HMF.

5-(hydroxymethyl)furan-2-carboxylic acid - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Hazard Class	IRRITANT

5-(hydroxymethyl)furan-2-carboxylic acid - Reference

Reference

1. [IF=4.411] Shengxin Yin et al."Comparison of Multiple Bioactive Constituents in the Corolla and Other Parts of Abelmoschus manihot."Molecules. 2021 Jan;26(7):1864

5-(hydroxymethyl)furan-2-carboxylic acid - Reference Information

biological activity

5-hydroxymethyll-2-furancarbonic acid is a major metabolite of 5-hydroxymethyl-2-furfural. 5-hydroxymethyll-2-furfural is an acid-catalyzed degradation product of sugars during the heating and storage of food, affecting its taste and physiological functions in the body.

Last Update：2024-04-09 20:49:11