5-BROMO-2-(BROMOMETHYL)-1,3-DIFLUOROBENZENE - Names and Identifiers
Name | 4-BROMO-2,6-DIFLUOROBENZYL BROMIDE
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Synonyms | 4-broMo-2,6-difluorobenzyl briMide 4-BROMO-2,6-DIFLUOROBENZYL BROMIDE 5-BROMO-2-(BROMOMETHYL)-1,3-DIFLUOROBENZENE Benzene, 5-broMo-2-(broMoMethyl)-1,3-difluoro- 5-Bromo-2-(bromomethyl)-1,3-difluorobenzene, alpha,4-Dibromo-2,6-difluorotoluene
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CAS | 162744-60-7
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InChI | InChI=1/C7H4Br2F2/c8-3-5-6(10)1-4(9)2-7(5)11/h1-2H,3H2 |
5-BROMO-2-(BROMOMETHYL)-1,3-DIFLUOROBENZENE - Physico-chemical Properties
Molecular Formula | C7H4Br2F2
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Molar Mass | 285.91 |
Density | 1.991 |
Boling Point | 244℃ |
Flash Point | 101℃ |
Vapor Presure | 0.0498mmHg at 25°C |
Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
Sensitive | Lachrymatory |
Refractive Index | 1.562 |
Physical and Chemical Properties | Sensitivity: Lachrymatory |
5-BROMO-2-(BROMOMETHYL)-1,3-DIFLUOROBENZENE - Risk and Safety
Hazard Symbols | C - Corrosive
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Hazard Note | Corrosive/Lachrymator |
5-BROMO-2-(BROMOMETHYL)-1,3-DIFLUOROBENZENE - Introduction
4-BROMO-2,6-DIFLUOROBENZYL BROMIDE is an organic compound with the chemical formula C8H5Br2F2. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: Colorless or yellowish liquid.
-Density: about 1.85 g/mL.
-Boiling point: About 220-222 ℃.
-Melting point: about 19-22 ℃.
-Solubility: Soluble in organic solvents such as ether and dichloromethane.
Use:
- 4-BROMO-2,6-DIFLUOROBENZYL BROMIDE can be used as an important reagent in organic synthesis for the synthesis of other organic compounds, especially organic compounds containing bromine and fluorine atoms.
-It can also be used to prepare organometallic compounds, such as platinum catalysts.
-In the pharmaceutical field, it may be used to produce certain pharmaceutical raw materials or intermediates.
Method:
- 4-BROMO-2,6-DIFLUOROBENZYL BROMIDE can be obtained by reacting dichloromethyl benzene BROMIDE with sodium tetrafluoroborate under alkaline conditions. The reaction mechanism involves the formation of sodium benzyl base and the exchange reaction with sodium tetrafluoroborate to obtain the target product.
Safety Information:
-Because it is an organic halogen compound, appropriate safety measures should be taken to avoid inhaling its vapor or touching the skin.
-Wear personal protective equipment such as protective gloves, goggles, and nurse's clothing when using or handling the compound.
-Avoid contact with strong oxidants or oxygen to avoid fire or explosion.
-In the event of accidental exposure or inhalation of large amounts of this compound, seek medical advice immediately and bring the compound's label or material safety data sheet to a medical facility.
Last Update:2024-04-09 21:04:16