5-Chloro-6-isopropoxypyridine-3-boronic acid
(5-Chloro-6-isopropoxypyridin-3-yl)boronic acid
CAS: 1150114-69-4
Molecular Formula: C8H11BClNO3
5-Chloro-6-isopropoxypyridine-3-boronic acid - Names and Identifiers
5-Chloro-6-isopropoxypyridine-3-boronic acid - Physico-chemical Properties
| Molecular Formula | C8H11BClNO3 |
| Molar Mass | 215.44 |
| Density | 1.28±0.1 g/cm3(Predicted) |
| Boling Point | 349.7±52.0 °C(Predicted) |
| pKa | 6.08±0.19(Predicted) |
| Storage Condition | 2-8°C |
| Sensitive | IRRITANT |
| MDL | MFCD12025983 |
5-Chloro-6-isopropoxypyridine-3-boronic acid - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | 22 - Harmful if swallowed |
5-Chloro-6-isopropoxypyridine-3-boronic acid - Introduction
boronic acid is an organic boron compound with the chemical formula C10H12BClNO3. The following is a description of some of its properties, uses, methods and safety information:
Nature:
-relative molecular mass: 227.47g/mol
-Appearance: Colorless or light yellow solid
-Melting point: approximately 120-125°C
-Solubility: Soluble in organic solvents such as dichloromethane, ethanol and dimethyl amide, slightly soluble in water
-Stability: relatively stable at room temperature, long-term storage when stored under dry conditions
Use:
- (Bi) boronic acid is an important organic synthesis intermediate, which can be used in organic synthesis reactions, such as nucleophilic substitution reactions and coupling reactions.
-It is usually used as a ligand for metal catalysts in organic synthesis and participates in cross-coupling reactions, such as SuZuki coupling and Stille coupling.
Preparation Method:
- (Br) boronic acid can be synthesized by oxidizing and decomposing (5-chloro-6-isopropoxypyridin-3-yl) nickel.
Safety Information:
- () boronic acid may be irritating to the eyes, skin and respiratory tract, so be careful to avoid contact when using it.
-Wear appropriate personal protective equipment such as lab gloves, goggles and protective clothing when using.
-In the operation to maintain good ventilation, and try to avoid inhalation or contact with the dust or steam of the compound.
-Waste disposal should be carried out in accordance with local environmental regulations and should not be dumped in the environment.
Nature:
-relative molecular mass: 227.47g/mol
-Appearance: Colorless or light yellow solid
-Melting point: approximately 120-125°C
-Solubility: Soluble in organic solvents such as dichloromethane, ethanol and dimethyl amide, slightly soluble in water
-Stability: relatively stable at room temperature, long-term storage when stored under dry conditions
Use:
- (Bi) boronic acid is an important organic synthesis intermediate, which can be used in organic synthesis reactions, such as nucleophilic substitution reactions and coupling reactions.
-It is usually used as a ligand for metal catalysts in organic synthesis and participates in cross-coupling reactions, such as SuZuki coupling and Stille coupling.
Preparation Method:
- (Br) boronic acid can be synthesized by oxidizing and decomposing (5-chloro-6-isopropoxypyridin-3-yl) nickel.
Safety Information:
- () boronic acid may be irritating to the eyes, skin and respiratory tract, so be careful to avoid contact when using it.
-Wear appropriate personal protective equipment such as lab gloves, goggles and protective clothing when using.
-In the operation to maintain good ventilation, and try to avoid inhalation or contact with the dust or steam of the compound.
-Waste disposal should be carried out in accordance with local environmental regulations and should not be dumped in the environment.
Last Update：2024-04-10 22:29:15
