5-METHOXY-1-INDANONE-3-ACETIC ACID, TECH . - Names and Identifiers
Name | 5-methoxy-1-indanone-3-acetic acid
|
Synonyms | 6-METHOXY-3-OXO-1-INDANACETIC ACID 5-methoxy-1-indanone-3-acetic acid 5-METHOXY-1-INDANONE-3-ACETIC ACID 5-Methoxy-1-oxoindane-3-acetic acid 5-methoxy-4-oxoindan-3-ylacetic acid 5-METHOXY-1-INDANONE-3-ACETIC ACID, TECH . 2,3-dihydro-6-methoxy-3-oxo-1h-indene-1-aceticaci 6-methoxy-3-oxo-2,3-dihydro-1h-indene-1-aceticacid 2,3-Dihydro-6-methoxy-3-oxo-1H-indene-1-acetic acid (6-methoxy-3-oxo-2,3-dihydro-1H-inden-1-yl)acetic acid
|
CAS | 24467-92-3
|
InChI | InChI=1/C12H12O4/c1-16-8-2-3-9-10(6-8)7(4-11(9)13)5-12(14)15/h2-3,6-7H,4-5H2,1H3,(H,14,15) |
5-METHOXY-1-INDANONE-3-ACETIC ACID, TECH . - Physico-chemical Properties
Molecular Formula | C12H12O4
|
Molar Mass | 220.22 |
Density | 1.286 |
Melting Point | 139-144 °C (lit.) |
Boling Point | 429℃ |
Flash Point | 171℃ |
Solubility | chloroform: soluble5%, clear, yellow-brown |
Vapor Presure | 4.11E-08mmHg at 25°C |
Storage Condition | Room Temprature |
Refractive Index | 1.569 |
5-METHOXY-1-INDANONE-3-ACETIC ACID, TECH . - Risk and Safety
WGK Germany | 3 |
RTECS | NK8225760 |
5-METHOXY-1-INDANONE-3-ACETIC ACID, TECH . - Introduction
5-methoxy-1-indanone-3-acetic acid is an organic compound with the chemical formula C13H14O4.
Nature:
-Appearance: Colorless to light yellow crystal or powder
-Melting point: about 83-86 degrees Celsius
-Boiling point: about 400 degrees Celsius
-Solubility: Slightly soluble in water, soluble in organic solvents such as ethanol and dichloromethane
-Typical keto and acidic characteristics
Use:
- 5-methoxy-1-indanone-3-acetic acid is an intermediate of organic synthesis, widely used in the fields of medicine and agrochemical.
-In medicine, it can be used to synthesize anti-inflammatory, analgesic and anti-cancer drugs.
-In agrochemistry, it can be used for synthetic pesticides and herbicides.
Method:
There are many synthesis methods of 5-methoxy-1-indanone-3-acetic acid. The following is a common preparation method:
1. First, methoxy styrene is reacted with methoxy lithium to generate 5-methoxy -1-indanone.
2. 5-methoxy-1-indanone is then reacted with sodium hydroxide/ethyl acetate to produce 5-methoxy-1-indanone-3-acetic acid.
Safety Information:
5-methoxy-1-indanone-3-acetic acid is relatively safe under general conditions of use, but the following matters still need to be paid attention:
-May be irritating to skin and eyes, avoid skin contact and inhalation when in contact.
-Wear appropriate protective equipment, such as chemical gloves and safety glasses.
-During operation and storage, avoid contact with oxidants, strong acids or strong bases.
-If ingested or inhaled, seek medical attention immediately.
Last Update:2024-04-09 21:01:54