5-METHOXY-2-METHYL INDOLE ACETIC ACID

5-METHOXY-2-METHYL INDOLE ACETIC ACID - Names and Identifiers

Name	5-Methoxy-2-methyl-3-indoleacetic acid
Synonyms	Indomethacin USP RC A Indomethacin EP Impurity B 5-METHOXY-2-METHYL INDOLE ACETIC ACID 5-Methoxy-2-methyl-3-indoleacetic acid 5-METHOXY-2-METHYL-3-INDOLEACETIC ACID 5-METHOXY-2-METHYLINDOLE-3-ACETIC ACID 5-methoxy-2-methylindol-3-ylacetic acid (5-methoxy-2-methyl-1H-indol-3-yl)acetate (5-methoxy-2-methyl-1H-indol-3-yl)acetic acid (5-METHOXY-2-METHYL-1H-INDOL-3-YL)-ACETIC ACID
CAS	2882-15-7
EINECS	220-734-7
InChI	InChI=1/C12H13NO3/c1-7-9(6-12(14)15)10-5-8(16-2)3-4-11(10)13-7/h3-5,13H,6H2,1-2H3,(H,14,15)/p-1

5-METHOXY-2-METHYL INDOLE ACETIC ACID - Physico-chemical Properties

Molecular Formula	C12H13NO3
Molar Mass	219.24
Density	1.1825 (rough estimate)
Melting Point	161-163 °C (lit.)
Boling Point	360.05°C (rough estimate)
Flash Point	226.1°C
Solubility	methanol: soluble
Vapor Presure	6.83E-09mmHg at 25°C
Appearance	Solid
Color	Off-white to light yellow or light beige
pKa	4.22±0.30(Predicted)
Storage Condition	2-8°C
Refractive Index	1.5270 (estimate)
MDL	MFCD00005618

5-METHOXY-2-METHYL INDOLE ACETIC ACID - Risk and Safety

Safety Description	24/25 - Avoid contact with skin and eyes.
WGK Germany	3
HS Code	29349990

5-METHOXY-2-METHYL INDOLE ACETIC ACID - Introduction

Acid (acid) is an organic compound with the chemical formula C12H13NO3. It is a white or off-white crystalline solid.

This compound is mainly an auxin analog, which has the properties of a plant growth regulator. It plays a role in regulating hormones in plant growth and development. In addition, it has a broad spectrum of fungicidal activity and can be used as a fungicide in agriculture.

The acid preparation method can be carried out through the following steps:

1. Preparation of N-animal oleoyl indole by condensation of Wuskeimide and animal oleic acid;
2. N-oleoyl indole reacts with acetic anhydride to produce N-oleoyl indole acetate;
3. N-oleoyl indole acetate reacts with silver oxide to give N-oleoyl indole carboxaldehyde;
4. N-animal oleoyl indole carboxaldehyde reacts with methanol to generate chromium acid.

Regarding safety information, acid has no obvious danger under normal use conditions. However, as a chemical, appropriate laboratory safety practices should be followed, including wearing appropriate protective equipment, avoiding inhalation, skin contact and eye contact, and avoiding contact with combustibles and oxidants. In case of accidental contact or accidental ingestion, please seek medical advice immediately.

Last Update：2024-04-10 22:29:15