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5-O-DESMETHYL OMEPRAZOLE

5-O-DESMETHYL OMEPRAZOLE

CAS: 151602-49-2

Molecular Formula: C16H17N3O3S

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5-O-DESMETHYL OMEPRAZOLE - Names and Identifiers

Name 5-O-DESMETHYL OMEPRAZOLE
Synonyms 5-Desmethylomeprazole
Esomeprazole impurity M
5-O-DESMETHYL OMEPRAZOLE
5-O-Desmethyl Omeprazole Metabolite
2-[[(4-Methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazol-6-ol
2-[[(4-Methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazol-5-ol
1H-Benzimidazol-6-ol,2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-
CAS 151602-49-2

5-O-DESMETHYL OMEPRAZOLE - Physico-chemical Properties

Molecular FormulaC16H17N3O3S
Molar Mass331.39
Density1.46±0.1 g/cm3(Predicted)
Melting Point238-240°C
Boling Point630.5±65.0 °C(Predicted)
Solubility Dimethylformamide, Dimethyl Sulfoxide, Ethanol, Methanol
AppearanceSolid
ColorLight-Yellow
pKa8.71±0.10(Predicted)
Storage Condition-20°C Freezer

5-O-DESMETHYL OMEPRAZOLE - Reference Information

Use this drug is a gastric proton pump inhibitor. Omeprazole can be concentrated around the secretory tubules of parietal cells after oral administration, conversion to sulfenamide derivatives. Its sulfur atom binds to the thiol group on the H ,K-ATPase, which inactivates the H pump and reduces gastric acid secretion. The drug can also increase gastric mucosal blood flow, is conducive to the treatment of ulcer disease. It is mainly used for gastric and duodenal ulcer, reflux esophagitis and zhuoai syndrome. It is also effective for patients with poor efficacy of H2 receptor blockers. 5-o-desmethylomeprazole is an impurity of Omeprazole.
Last Update:2024-04-09 15:16:55
5-O-DESMETHYL OMEPRAZOLE
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CAS: 151602-49-2
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View History
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