5-Pyrimidinecarboxylic acid, 2-amino-4-(4-fluorophenyl)-, methyl ester
Methyl 2-amino-4-(4-fluorophenyl)-pyrimidine-5-carboxylate
CAS: 1133115-54-4
Molecular Formula: C12H10FN3O2
5-Pyrimidinecarboxylic acid, 2-amino-4-(4-fluorophenyl)-, methyl ester - Names and Identifiers
5-Pyrimidinecarboxylic acid, 2-amino-4-(4-fluorophenyl)-, methyl ester - Physico-chemical Properties
| Molecular Formula | C12H10FN3O2 |
| Molar Mass | 247.23 |
| Density | 1.332±0.06 g/cm3(Predicted) |
| Boling Point | 474.0±55.0 °C(Predicted) |
| pKa | 1.56±0.10(Predicted) |
| Storage Condition | 2-8℃ |
| Sensitive | IRRITANT |
| MDL | MFCD11855873 |
5-Pyrimidinecarboxylic acid, 2-amino-4-(4-fluorophenyl)-, methyl ester - Introduction
Methyl 2-amino-4-(4-fluorophenyl)-pyrimidine-5-carboxylate is an organic compound with the chemical formula C12H9FN4O2. It had the appearance of a white crystalline solid.
This compound has a variety of properties and uses. First of all, it is an aromatic amine compound with a certain solubility and melting point. Secondly, it is an ester compound with certain stability and solubility. In addition, its molecule contains amino and carboxyl groups, which makes it have certain reactivity and function in chemical reactions.
In terms of application, Methyl 2-amino-4-(4-fluorophenyl)-pyrimidine-5-carboxylate is widely used in the pharmaceutical field and organic synthesis. As an intermediate compound, it is often used in the synthesis of other compounds or drugs. For example, it can be used in the synthesis of antitumor drugs and antiviral drugs.
regarding the preparation method, the preparation method of Methyl 2-amino-4-(4-fluorophenyl)-pyrimidine-5-carboxylate is relatively complicated and generally requires the help of organic synthesis technology. A common preparation method is to obtain 2-amino -4-(4-fluorophenyl) pyrimidine by reacting 4-fluorobenzaldehyde and 2-amino-4-cyanopyrimidine, and then to convert 2-amino -4-(4-fluorophenyl) pyrimidine into its ester compound by esterification.
When using Methyl 2-amino-4-(4-fluorophenyl)-pyrimidine-5-carboxylate, you need to pay attention to some safety information. First of all, because it is an organic compound, it has certain toxicity and danger, so it is necessary to pay attention to safety protection measures during operation and storage. Secondly, it should be stored in a dry, ventilated and light-proof environment, avoiding contact with air, moisture, sunlight, etc. In addition, it is strictly forbidden to contact with strong oxidants and strong acidic substances to avoid dangerous reactions. When disposing of waste, it should be disposed of in accordance with relevant laws and regulations.
This compound has a variety of properties and uses. First of all, it is an aromatic amine compound with a certain solubility and melting point. Secondly, it is an ester compound with certain stability and solubility. In addition, its molecule contains amino and carboxyl groups, which makes it have certain reactivity and function in chemical reactions.
In terms of application, Methyl 2-amino-4-(4-fluorophenyl)-pyrimidine-5-carboxylate is widely used in the pharmaceutical field and organic synthesis. As an intermediate compound, it is often used in the synthesis of other compounds or drugs. For example, it can be used in the synthesis of antitumor drugs and antiviral drugs.
regarding the preparation method, the preparation method of Methyl 2-amino-4-(4-fluorophenyl)-pyrimidine-5-carboxylate is relatively complicated and generally requires the help of organic synthesis technology. A common preparation method is to obtain 2-amino -4-(4-fluorophenyl) pyrimidine by reacting 4-fluorobenzaldehyde and 2-amino-4-cyanopyrimidine, and then to convert 2-amino -4-(4-fluorophenyl) pyrimidine into its ester compound by esterification.
When using Methyl 2-amino-4-(4-fluorophenyl)-pyrimidine-5-carboxylate, you need to pay attention to some safety information. First of all, because it is an organic compound, it has certain toxicity and danger, so it is necessary to pay attention to safety protection measures during operation and storage. Secondly, it should be stored in a dry, ventilated and light-proof environment, avoiding contact with air, moisture, sunlight, etc. In addition, it is strictly forbidden to contact with strong oxidants and strong acidic substances to avoid dangerous reactions. When disposing of waste, it should be disposed of in accordance with relevant laws and regulations.
Last Update：2024-04-09 21:49:45
