5-azido-Pentanoic acid
5-azido-Pentanoic acid
CAS: 79583-98-5
Molecular Formula: C5H9N3O2
5-azido-Pentanoic acid - Names and Identifiers
| Name | 5-azido-Pentanoic acid |
| Synonyms | 5-Azidovaleric acid d-Azidovaleric acid 5-Azidopentanoic acid 5-AZIDO-PENTANOIC ACID 5-azido-Pentanoic acid 5-AZIDO-VALERIANIC ACID Pentanoic acid, 5-azido- 5-Azidopentanoic acid - A1942 |
| CAS | 79583-98-5 |
| InChIKey | SBZDIRMBQJDCLB-UHFFFAOYSA-N |
5-azido-Pentanoic acid - Physico-chemical Properties
| Molecular Formula | C5H9N3O2 |
| Molar Mass | 143.145 |
| Density | 1.142 |
| Boling Point | 85°C/0.01mmHg(lit.) |
| Appearance | clear liquid |
| Color | Colorless to Red to Green |
| BRN | 1706398 |
| Storage Condition | -20°C |
| Refractive Index | 1.4640-1.4680 |
5-azido-Pentanoic acid - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | 40 - Limited evidence of a carcinogenic effect |
| Safety Description | 36/37 - Wear suitable protective clothing and gloves. |
| WGK Germany | 3 |
| HS Code | 29299090 |
5-azido-Pentanoic acid - Introduction
5-azido-pentanoic acid is an organic compound with the chemical formula C5H9N3O2. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: 5-azido-Pentanoic acid is a colorless crystalline powder or a white solid.
-Solubility: It is not easily soluble in water, but can be dissolved in organic solvents such as methanol, ethanol and dichloromethane.
-Stability: 5-azido-Pentanoic acid can exist stably at room temperature, but it is sensitive to light and heat.
Use:
-Organic synthesis: 5-azido-Pentanoic acid, as an azide compound, can be used as a strong electron activation reagent in organic synthesis. It can participate in specific reactions, such as cyclization and coupling reactions of alkynes. In addition, it can also be used for the synthesis of fluorescent dyes and bioactive molecules.
-Research: Due to its special properties, 5-azido-Pentanoic acid is often used in biological and chemical research, such as biomarkers, drug delivery and materials science.
Preparation Method:
- 5-azido-Pentanoic acid can be obtained by the synthetic reaction of the substrate azido-iodo-pentanoic acid (4-azido-iodo-butyanoic acid). The specific synthesis method can be to react the substrate with an alkaline substrate (such as sodium chloride or silver triflate) in an organic solvent to generate 5-azido-Pentanoic acid.
Safety Information:
- 5-azido-Pentanoic acid needs to avoid light and high temperature during operation and storage to prevent possible decomposition.
-It is an explosive chemical and should strictly follow safe operating procedures to avoid contact with flammable materials or exposure to open flames.
-Wear appropriate personal protective equipment, such as gloves and goggles, and maintain a well-ventilated laboratory environment.
-When disposing of waste, it should be handled and disposed in accordance with local environmental regulations to avoid potential environmental and health hazards.
Nature:
-Appearance: 5-azido-Pentanoic acid is a colorless crystalline powder or a white solid.
-Solubility: It is not easily soluble in water, but can be dissolved in organic solvents such as methanol, ethanol and dichloromethane.
-Stability: 5-azido-Pentanoic acid can exist stably at room temperature, but it is sensitive to light and heat.
Use:
-Organic synthesis: 5-azido-Pentanoic acid, as an azide compound, can be used as a strong electron activation reagent in organic synthesis. It can participate in specific reactions, such as cyclization and coupling reactions of alkynes. In addition, it can also be used for the synthesis of fluorescent dyes and bioactive molecules.
-Research: Due to its special properties, 5-azido-Pentanoic acid is often used in biological and chemical research, such as biomarkers, drug delivery and materials science.
Preparation Method:
- 5-azido-Pentanoic acid can be obtained by the synthetic reaction of the substrate azido-iodo-pentanoic acid (4-azido-iodo-butyanoic acid). The specific synthesis method can be to react the substrate with an alkaline substrate (such as sodium chloride or silver triflate) in an organic solvent to generate 5-azido-Pentanoic acid.
Safety Information:
- 5-azido-Pentanoic acid needs to avoid light and high temperature during operation and storage to prevent possible decomposition.
-It is an explosive chemical and should strictly follow safe operating procedures to avoid contact with flammable materials or exposure to open flames.
-Wear appropriate personal protective equipment, such as gloves and goggles, and maintain a well-ventilated laboratory environment.
-When disposing of waste, it should be handled and disposed in accordance with local environmental regulations to avoid potential environmental and health hazards.
Last Update：2024-04-09 20:52:54
