6-((tert-butyldimethylsilyl)oxy)benzofuran-3(2H)-one

6-((tert-butyldimethylsilyl)oxy)benzofuran-3(2H)-one - Names and Identifiers

Name	6-((tert-butyldimethylsilyl)oxy)benzofuran-3(2H)-one
Synonyms	6-((tert-butyldimethylsilyl)oxy)benzofuran-3(2H)-one 3(2H)-Benzofuranone, 6-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-
CAS	299912-77-9

6-((tert-butyldimethylsilyl)oxy)benzofuran-3(2H)-one - Physico-chemical Properties

Molecular Formula	C14H20O3Si
Molar Mass	264.3923
Storage Condition	RT, sealed, dark

6-((tert-butyldimethylsilyl)oxy)benzofuran-3(2H)-one - Upstream Downstream Industry

Downstream Products

Methyl benzofuran-6-carboxylate
1-BENZOFURAN-6-OL
1-BENZOFURAN-6-CARBALDEHYDE

6-((tert-butyldimethylsilyl)oxy)benzofuran-3(2H)-one - Introduction

6-((tert-butyldimethylsilyl)oxy)benzofuran-3(2H)-one is also known as 6-((tert-butyldimethylsilyl)oxy)benzofuran-3(2H)-one.

Nature:
-Appearance: White to light yellow solid
-Molecular formula: C16H22O3Si
-Molecular weight: 294.43g/mol
-Melting point: about 40-42°C
-Boiling point: about ninety
-Solubility: Soluble in non-polar organic solvents such as dichloromethane and carbon disulfide

Use:
This compound is often used as an intermediate in organic synthesis. Because of its special structure, it can play a protective role in the synthesis process, which is used to protect the active functional groups such as alcohol, carboxylic acid or hydroxyl from the influence of external conditions. It stabilizes high temperature and acidic conditions, facilitates the reaction, and can be easily removed when needed.

Preparation Method:
This compound can be prepared by reacting tert-butyldimethylchlorosilane with benzofuran-3 (2H)-one. The reaction is typically carried out under an inert atmosphere and under basic conditions.

Safety Information:
There is less information on the safety of this compound, but basic laboratory safety measures, such as wearing appropriate protective gloves, glasses and laboratory coats, should be taken when handling or using it. Avoid inhalation, ingestion or contact with skin. Avoid contact with strong oxidants. If necessary, refer to the specific safety data form.

Last Update：2024-04-10 22:29:15