6-氧-2,3-二苯基-4-吗啉羧酸酯

6-氧-2,3-二苯基-4-吗啉羧酸酯 - Names and Identifiers

Name	tert-butyl (2S,3R)-(+)-6-oxo-2,3-diphenyl-4-morph
Synonyms	(2S,3R)-tert-Butyl (5R,6S)-N-Boc-5,6-diphenyl-2-morpholinone (2S,3R)-(+)-N-Boc-6-oxo-2,3-diphenylMorpholine tert-butyl (2S,3R)-(+)-6-oxo-2,3-diphenyl-4-morph tert-butyl 6-oxo-2,3-diphenylmorpholine-4-carboxylate tert-butyl (2S,3R)-6-oxo-2,3-diphenylMorpholine-4-carboxylate tert-butyl (2S,3R)-6-oxo-2,3-diphenylmorpholine-4-carboxylate (2S,3R)-tert-Butyl 6-oxo-2,3- diphenylmorpholine-4-carboxylate tert-Butyl (2S,3R)-(+)-6-oxo-2,3-diphenyl-4-morpholinecarboxylate (2S, 3R) - (+) - N- t-butoxycarbonyl-6-oxo-2,3-diphenyl-Morpholine (2S,3R)-6-Oxo-2,3-diphenyl-morpholine-4-carboxylic acid tert-butyl ester
CAS	112741-50-1
EINECS	627-150-5
InChI	InChI=1/C21H23NO4/c1-21(2,3)26-20(24)22-14-17(23)25-19(16-12-8-5-9-13-16)18(22)15-10-6-4-7-11-15/h4-13,18-19H,14H2,1-3H3
InChIKey	MRUKRSQUUNYOFK-MOPGFXCFSA-N

6-氧-2,3-二苯基-4-吗啉羧酸酯 - Physico-chemical Properties

Molecular Formula	C21H23NO4
Molar Mass	353.41
Density	1.175±0.06 g/cm3(Predicted)
Melting Point	206°C (dec.)(lit.)
Boling Point	509.6±50.0 °C(Predicted)
Specific Rotation(α)	86 º (c=5.5 in methylene chloride)
Flash Point	262°C
Vapor Presure	1.67E-10mmHg at 25°C
Appearance	White powder
pKa	-3.28±0.60(Predicted)
Storage Condition	2-8°C
Refractive Index	1.561

6-氧-2,3-二苯基-4-吗啉羧酸酯 - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S37/39 - Wear suitable gloves and eye/face protection
WGK Germany	3

6-氧-2,3-二苯基-4-吗啉羧酸酯 - Introduction

(2S,3R)-N-tert-butoxycarbonyl-2,3-diphenylmorpholin-6-one, also known as (2S,3R)-N-tert-butoxycarbonyl-2,3-diphenylmorpholin-6-one, is an organic compound. The following is a description of the properties, uses, preparation and safety information of the compound:

Nature:
-Appearance: A white crystalline powder or crystal
-Molecular formula: C24H25NO3
-Molecular weight: 375.46g/mol
-Melting point: 82-85°C
-Solubility: Soluble in alcohol and ketone solvents

Use:
(2S,3R)-N-tert-butoxycarbonyl-2, 3-diphenylmorpholin-6-one is an intermediate compound, which is often used in the synthesis of biologically active compounds in organic synthesis. It can be used to prepare drugs, pharmaceutical intermediates, functional materials, etc.

Preparation Method:
A common preparation method is as follows:
First, 2,3-diphenylmorpholine and tert-butoxyacid (tert-butyl acid) are reacted under specific conditions to produce a tert-butoxycarbonylation product. The t-butoxycarbonylation product is then acylated by the addition of an acylating agent such as DCC and a suitable solvent to give the desired compound.

Safety Information:
(2S,3R)-N-tert-butoxycarbonyl-2, 3-diphenylmorpholin-6-one has not been widely studied, so the understanding of its safety is limited. During handling and use, it is recommended to follow general laboratory safety practices, such as wearing gloves, eye protection and protective clothing. In addition, care should be taken to prevent inhalation, ingestion, or contact with skin and eyes. If contact occurs, flush immediately with plenty of water and seek medical help.

Last Update：2024-04-09 21:01:54