6-Bromo-2-oxo-2H-chromene-3-carboxylic acid ethyl ester

6-Bromo-2-oxo-2H-chromene-3-carboxylic acid ethyl ester - Names and Identifiers

Name	ethyl 6-bromo-2-oxo-2H-chromene-3-carboxylate
Synonyms	ETHYL 6-BROMOCOUMARIN-3-CARBOXYLATE ethyl 6-bromo-2-oxochromene-3-carboxylate ethyl 6-bromo-2-oxo-chromene-3-carboxylate Ethyl 6-bromo-2-oxo-2H-chromene-3-carboxylate ethyl 6-bromo-2-oxo-2H-chromene-3-carboxylate ethyl 6-broMo-2-oxo-2H-chroMene-3-carboxylate 6-Bromocoumarin-3-carboxylic Acid Ethyl Ester 6-bromo-2-oxo-3-chromenecarboxylic acid ethyl ester 6-bromo-2-keto-chromene-3-carboxylic acid ethyl ester 6-Bromo-2-oxo-2H-chromene-3-carboxylic acid ethyl ester 2H-1-Benzopyran-3-carboxylic acid, 6-bromo-2-oxo-, ethyl ester
CAS	2199-90-8
InChI	InChI=1/C12H9BrO4/c1-2-16-11(14)9-6-7-5-8(13)3-4-10(7)17-12(9)15/h3-6H,2H2,1H3

6-Bromo-2-oxo-2H-chromene-3-carboxylic acid ethyl ester - Physico-chemical Properties

Molecular Formula	C12H9BrO4
Molar Mass	297.1
Density	1.602g/cm³
Melting Point	164 °C
Boling Point	426.4°C at 760 mmHg
Flash Point	211.7°C
Vapor Presure	1.77E-07mmHg at 25°C
Appearance	powder to crystal
Color	White to Orange to Green
Storage Condition	Sealed in dry,Room Temperature
Refractive Index	1.595
MDL	MFCD00124584

6-Bromo-2-oxo-2H-chromene-3-carboxylic acid ethyl ester - Introduction

ethyl is an organic compound with the chemical formula C12H9BrO4. It is a white crystalline solid with a distinctive odor.

This compound is often used as an intermediate in organic synthesis and can be used to synthesize different types of compounds. It can be used as a raw material in the fields of pesticide, medicine and cosmetics. Specifically, it can be used to synthesize active compounds containing coumarin structures for the research of antibacterial and anticancer drugs.

The method for preparing ethyl L is obtained by the catalytic reaction of brominated coumarin with Acetyl bromide in the presence of a base. First, Acetyl bromide is added dropwise to an aqueous solution of sodium carbonate in the presence of a base, and then coumarin bromide is added. After the completion of the reaction, the target product is finally obtained through the steps of acidification and extraction.

Regarding its safety information, ethyl may have an irritating effect on the eyes, skin and respiratory tract. Therefore, appropriate protective equipment such as gloves, goggles and respiratory protection must be worn during use. In addition, make sure to operate in a well-ventilated area and take care to avoid contact with strong oxidants. During storage, it should be kept in a cool, dry and ventilated place, away from fire and combustibles.

Last Update：2024-04-09 21:54:55