6-Chloro-5-(trifluoromethyl)pyridin-2-amine

6-Chloro-5-(trifluoromethyl)pyridin-2-amine - Names and Identifiers

Name	6-Chloro-5-(trifluoromethyl)pyridin-2-amine
Synonyms	Benzoylchloride,5-(dimethylamino)- 2-Amino-6-chloro-5-trifluoromethylpyridine 6-chloro-5-(trifluoromethyl)pyridin-2-amine 6-Chloro-5-(trifluoromethyl)pyridin-2-amine 6-Chloro-5-trifluoromethyl-pyridin-2-ylamine 2-Pyridinamine, 6-chloro-5-(trifluoromethyl)- 3-chloro-4-(trifluoromethyl)aniline79456-28-3 2H-Pyrrol-2-one,1,5-dihydro-3-hydroxy-4-[3-methyl-4-(phenylmethoxy)benzoyl]-1-[3-(4-morpholinyl)propyl]-5-(9-pyridinyl)-
CAS	79456-28-3

6-Chloro-5-(trifluoromethyl)pyridin-2-amine - Physico-chemical Properties

Molecular Formula	C6H4ClF3N2
Molar Mass	196.56
Density	1.507±0.06 g/cm3(Predicted)
Boling Point	264.5±40.0 °C(Predicted)
pKa	0.51±0.37(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2–8 °C

6-Chloro-5-(trifluoromethyl)pyridin-2-amine - Risk and Safety

UN IDs	2811
Hazard Class	6.1
Packing Group	Ⅲ

6-Chloro-5-(trifluoromethyl)pyridin-2-amine - Introduction

6-Chloro-5-(trifluoromethyl)pyridin-2-amine is an organic compound whose chemical formula is C6H3ClF3N2.

Nature:
6-Chloro-5-(trifluoromethyl)pyridin-2-amine is a white solid that can exist as crystals at room temperature. It has low solubility in water, but better solubility in organic solvents. Its melting and boiling points are 85-88°C and 247-248°C, respectively.

Use:
6-Chloro-5-(trifluoromethyl)pyridin-2-amine is commonly used as an intermediate in organic synthesis. It can be used in the synthesis of pesticides, pharmaceuticals and other organic compounds. Due to its special chemical structure and properties, it has a wide range of applications in agriculture, medicine and materials science.

Preparation Method:
6-Chloro-5-(trifluoromethyl)pyridin-2-amine can be prepared by a substitution reaction of the amino group on the pyridine molecule. One common method is to react a pyridine dinitro compound with a trifluoromethyl-substituted reagent to form the desired product under reductive conditions.

Safety Information:
6-Chloro-5-(trifluoromethyl)pyridin-2-amine should be considered an organic compound and requires proper disposal. During use, wear appropriate personal protective equipment, including glasses, gloves, lab clothes, etc. At the same time, the operation should be carried out in a well-ventilated place to avoid contact with the skin and inhalation of its vapors. In case of accidental contact or discomfort, seek medical attention immediately. For the handling and disposal of this compound, the relevant regulations and guidelines should be followed.

Last Update：2024-04-09 21:11:58