6-Chloro-o-toluenesulfonylchoride

6-Chloro-o-toluenesulfonylchoride - Names and Identifiers

Name	2-Chloro-6-methylbenzenesulfonyl chloride
Synonyms	5300-37-2 6-Chloro-o-toluenesulfonylchoride 6-Chloro-o-toluenesulfonyl chloride 2-CHLORO-6-METHYLBENZENESULFONYL CHLORIDE 2-Chloro-6-methylbenzenesulfonyl chloride 6-Chloro-2-methylbenzenesulfonyl Chloride 2-CHLORO-6-METHYLBENZENESULPHONYL CHLORIDE 2-chloro-6-Methylbenzene-1-sulfonyl chloride Benzenesulfonyl chloride, 2-chloro-6-methyl-
CAS	25300-37-2
InChI	InChI=1/C7H6Cl2O2S/c1-5-3-2-4-6(8)7(5)12(9,10)11/h2-4H,1H3

6-Chloro-o-toluenesulfonylchoride - Physico-chemical Properties

Molecular Formula	C7H6Cl2O2S
Molar Mass	225.09
Density	1.458±0.06 g/cm3(Predicted)
Boling Point	132-134°C 0,5mm
Flash Point	132-134°C/0.5mm
Vapor Presure	0.001mmHg at 25°C
BRN	2722659
Storage Condition	Inert atmosphere,Room Temperature
Sensitive	Moisture Sensitive
Refractive Index	1.5810
MDL	MFCD00051767

6-Chloro-o-toluenesulfonylchoride - Risk and Safety

Risk Codes	R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R34 - Causes burns R36/37 - Irritating to eyes and respiratory system.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S27 - Take off immediately all contaminated clothing. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
UN IDs	3265
Hazard Class	8
Packing Group	II

6-Chloro-o-toluenesulfonylchoride - Introduction

chloride is an organic compound with the chemical formula C7H6ClClO2S, commonly abbreviated as CMBS. It is a white solid crystal, insoluble in water at room temperature.

The compounds are commonly used as reagents and intermediates in organic synthesis reactions. It has an electrophilic sulfonyl chloride functional group that can undergo substitution reactions with nucleophiles and is commonly used in the synthesis of target molecules with a benzenesulfonyl group. It is also widely used in medicine for the synthesis of bioactive molecules and drugs.

The preparation method of chloride is usually obtained by reacting p-methylbenzenesulfonyl chloride with thionyl chloride. The reaction is usually carried out at room temperature and the 6-methyl position is selectively substituted.

When using chloride, be aware of its toxicity and irritation. It is a corrosive compound that can cause severe chemical burns on contact with the skin and eyes. Wear appropriate protective gloves, glasses and protective clothing during operation. In addition, it should also be away from fire and oxidizing agents, avoid contact with flammable substances. When stored, it should be kept in a sealed, dry and cool place.

Last Update：2024-04-09 02:00:44