6-Chloropyridazine-4-carboxylate

6-Chloropyridazine-4-carboxylate - Names and Identifiers

Name	4-Pyridazinecarboxylicacid, 6-chloro-, methyl ester
Synonyms	6-Chloropyridazine-4-carboxylate methyl6-chloropyridazine-4-carboxylate methyl 6-chloropyridazine-4-carboxylate 6-Chloro-pyridazine-4-carboxylic acid Methyl ester 4-Pyridazinecarboxylicacid, 6-chloro-, methyl ester 4-Pyridazinecarboxylic Acid, 6-Chloro-, Methyl Ester 4-Pyridazinecarboxylic acid, 6-chloro-, Methyl ester 3-Chloro-5-(methoxycarbonyl)pyridazine, 3-Chloro-5-(methoxycarbonyl)-1,2-diazine
CAS	1093860-48-0
EINECS	200-258-5

6-Chloropyridazine-4-carboxylate - Physico-chemical Properties

Molecular Formula	C6H5ClN2O2
Molar Mass	172.57
Density	1.372±0.06 g/cm3(Predicted)
Boling Point	326.9±22.0 °C(Predicted)
Appearance	Liquid or Low Melting Solid
Color	Colorless to yellow to pale brown
pKa	-1.33±0.10(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C

6-Chloropyridazine-4-carboxylate - Introduction

Methyl 6-chloropyridazine-4-carboxylate is an organic compound whose chemical formula is C6H6ClNO2. The following is a description of the properties, uses, preparation and safety information of the compound:

Nature:
1. Appearance: 6-chloropyridazine-4-carboxylic acid methyl ester is a colorless to light yellow liquid.
2. solubility: soluble in organic solvents, such as alcohols and ethers.
3. Melting point and boiling point: the melting point is about -12°C, and the boiling point is about 206°C.
4. storage stability: should be stored in a cool, dry, well-ventilated place, away from oxidants and fire.

Use:
1. 6-chloropyridazine-4-carboxylic acid methyl ester can be used as an intermediate in organic synthesis for the synthesis of other compounds.
2. It can be used as a precursor for pesticides and herbicides in the agricultural field.
3. In the field of medicine, it can be used to prepare some drugs.

Preparation Method:
The preparation method of 6-chloropyridazine-4-carboxylic acid methyl ester can be obtained by reacting pyridazine chloride with formic acid ester. Specific steps are as follows:
1. In a suitable reaction vessel, mix pyridazine chloride and formate in molar proportions.
2. The reaction mixture is stirred under an appropriate temperature condition to allow the reaction to proceed.
3. Control the reaction time and temperature to complete the reaction.
4. After the reaction, the product was isolated and purified.

Safety Information:
1. 6-chloropyridazine-4-carboxylic acid methyl ester is a chemical substance and should be handled with caution to avoid skin contact and inhalation of gas or solution.
2. when using, should wear appropriate protective equipment, such as gloves, goggles and protective mask.
3. in the process of operation should maintain good ventilation conditions.
4. If taken by mistake or in contact with skin or eyes, rinse immediately with plenty of water and seek medical help.
5. During storage and handling, avoid storage or contact with oxidants and combustibles to prevent the risk of fire and explosion.

Last Update：2024-04-09 15:17:50