6-Difluoroindole-2-carboxylic acid

6-Difluoroindole-2-carboxylic acid - Names and Identifiers

Name	4,6-Difluoroindole-2-carboxylic acid
Synonyms	T56 BMJ CVQ FF HF 4,6-Difluoro-2-carboxy Indole 6-Difluoroindole-2-carboxylic acid 4,6-Difluoroindole-2-carboxylic acid 4,6-DIFLUOROINDOLE-2-CARBOXYLIC ACID 4,6-difluoro-1H-indole-2-carboxylicaci 4,6-DIFLUORO-1H-INDOLE-2-CARBOXYLIC ACID 4,6-difluoro-1H-indole-2-carboxylic acid 1H-Indole-2-carboxylic acid, 4,6-difluoro- 1H-indole-2-carboxylic acid, 4,6-difluoro-
CAS	247564-66-5
InChI	InChI=1/C9H5F2NO2/c10-4-1-6(11)5-3-8(9(13)14)12-7(5)2-4/h1-3,12H,(H,13,14)

6-Difluoroindole-2-carboxylic acid - Physico-chemical Properties

Molecular Formula	C9H5F2NO2
Molar Mass	197.14
Density	1.605±0.06 g/cm3(Predicted)
Boling Point	414.7±40.0 °C(Predicted)
Flash Point	204.6°C
Vapor Presure	1.28E-07mmHg at 25°C
pKa	4.25±0.30(Predicted)
Storage Condition	Sealed in dry,Room Temperature
Sensitive	Light Sensitive
Refractive Index	1.661

6-Difluoroindole-2-carboxylic acid - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S37/39 - Wear suitable gloves and eye/face protection

6-Difluoroindole-2-carboxylic acid - Introduction

acid is an organic compound with the chemical formula C9H5F2NO2. The following is a description of its nature, use, preparation and safety information:

Properties: 4 acid is a white solid with a unique chemical structure. Its melting point is 142-145 ° C. It is a weak acid that can be dissolved in some organic solvents, such as alcohols, esters and dichloromethane.

use: 4, acid has a wide range of applications in organic synthesis. It can be used as a pharmaceutical intermediate for the synthesis of various complex organic compounds. It can also be used in the preparation of drugs and pesticides containing indole structures.

preparation method: 4, acid can be prepared by a variety of synthetic methods. A common method is to react 2,4-difluoroindole with trifluoromethoxycarboxylic anhydride, followed by deprotection to give the desired product.

Safety information: When handling 4, acid, necessary laboratory safety measures need to be taken. It may cause irritation to the eyes, skin, and respiratory tract, so personal protective equipment such as lab gloves, goggles, and protective masks should be used. At the same time, it should be kept away from fire sources and oxidants, and stored in a sealed container to avoid contact with air or water. Observe relevant laboratory safety regulations and procedures when using or handling this compound.

Last Update：2024-04-09 21:11:58