Name | 6-Methoxyldihydrochelerythrine chloride |
Synonyms | Angoline hydrochloride 6-Methoxyldihydrochelerythrine chloride |
CAS | 1071676-04-4 |
Molecular Formula | C22H22ClNO5 |
Molar Mass | 415.87 |
Melting Point | 267-268 °C |
Storage Condition | 2-8℃ |
biological activity | Angoline hydrochloride is a potent and selective inhibitor of the IL6/STAT3 signaling pathway, the IC50 was 11.56 μm. Angoline hydrochloride inhibits STAT3 phosphorylation and its target gene expression, and inhibits cancer cell proliferation. |
Target | IC50: 11.56 μm (IL6/STAT3 signaling pathway) |