6-O-Desmethyl Donepezil-d5 - Names and Identifiers
6-O-Desmethyl Donepezil-d5 - Physico-chemical Properties
Molecular Formula | C23H27NO3
|
Molar Mass | 365.46538 |
Melting Point | 54-56°C |
Solubility | Chloroform (Slightly), Methanol (Slightly) |
Appearance | Solid |
Color | White to Pale-Yellow |
Storage Condition | -20°C Freezer |
6-O-Desmethyl Donepezil-d5 - Introduction
6-O-Desmethyl Donepezil-d5 (6-o-demethyldonepezil-d5) is a compound with special properties. It is based on a structural derivative of donepezil, in which the desmethyl group is replaced by deuterium, so the label-d5 indicates that there are five deuterium substitutions.
6-O-Desmethyl Donepezil-d5 is a compound with a six-membered oxa ring, which can be used as an important reagent in chemical research and drug development. It is mainly used in the pharmacokinetic and pharmacokinetic studies of donepezil drugs. It can metabolize donepezil in the body, and the 6-O-Desmethyl Donepezil-d5 labeled with Deuterium isotopes can track and quantitatively analyze the metabolism of drugs, this helps researchers understand the activity and metabolic mechanisms of drugs in the body.
The method of preparing 6-O-Desmethyl Donepezil-d5 usually involves organic synthetic chemistry. First, Donepezil is converted into 6-O-Desmethyl Donepezil through a series of reactions, and then deuterium gas or its representative compound is reacted with 6-O-Desmethyl Donepezil to obtain 6-O-Desmethyl Donepezil-d5.
When using and handling 6-O-Desmethyl Donepezil-d5, you need to pay attention to its safety. Since it is a chemical reagent, it should follow laboratory standards for safe operation and handle it correctly according to the information provided in the relevant safety data sheet. In terms of storage, the compound should be stored in a dry, cool place and avoid contact with oxygen, moisture and fire sources. Specific safety information on its toxicity and danger should be provided in the substance's safety data sheet. When using and handling chemicals, always ensure that the correct procedures and laboratory standards are followed.
Last Update:2024-04-09 21:04:16