6-chloro-5-nitronicotinoyl chloride - Names and Identifiers
6-chloro-5-nitronicotinoyl chloride - Physico-chemical Properties
6-chloro-5-nitronicotinoyl chloride - Upstream Downstream Industry
6-chloro-5-nitronicotinoyl chloride - Introduction
It is an organic compound with the chemical structure C6H2ClN3O3Cl. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: chloride is a colorless or light yellow crystalline powder.
-Melting point: about 105-107 ℃.
-Boiling point: About 295 ℃.
-Solubility: It is soluble in common organic solvents (such as ether, methanol, dichloromethane, etc.), but has low solubility in water.
Use:
-Chemical synthesis: chloride can be used as a reagent in organic synthesis to find the preparation route of various compounds, such as drug intermediates, pesticide intermediates, etc.
-Biological activity: It is also used as an active substance in the field of biological activity and new drug discovery.
Method:
Generally, chloride is prepared by the following steps:
1. The first preparation of 5-Nitro nicotinic acid: the reaction of nicotinic acid with nitric acid, generating 5-Nitro nicotinic acid.
2. React 5-Nitro nicotinic acid with attapulgous acid to generate 6-chloro -5-Nitro nicotinic acid.
3. Finally, 6-chloro-5-nitronicotinic acid is reacted with thionyl chloride to generate chloride.
Safety Information:
-is an organic compound, which is irritating and corrosive.
-Use protective equipment to avoid direct contact with skin, eyes and respiratory tract.
-Pay attention to protective measures during operation, including good ventilation and avoiding inhalation of dust.
-Keep the storage container sealed, away from fire and high temperature environment to prevent the risk of fire and explosion.
-Before discarding waste, please refer to local regulations for proper treatment and disposal.
Last Update：2024-04-09 21:00:56