6-maleimidocaproic acid
6-maleimidocaproic acid
CAS: 55750-53-3
Molecular Formula: C10H13NO4
6-maleimidocaproic acid - Names and Identifiers
| Name | 6-maleimidocaproic acid |
| Synonyms | Mal-(CH2)5-COOH (EMCA) 6-maleimidocaproic acid 6-Maleimidohexanoic acid N-(5-CARBOXYPENTYL)MALEIMIDE N-MALEOYL-6-AMINO-CAPROIC ACID N-EPSILON-MALEIMIDOCAPROIC ACID N-(5-Carboxy-n-pentyl)MaleiMide 2,5-Dihydro-2,5-dioxo-1H-pyrrole-1-hexanoic Acid 6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanoic acid 6-Maleimidocaproic acid, N-(5-Carboxypentyl)maleimide, N-Maleoyl-6-aminocaproic acid 6-Maleimidohexanoic acid,6-Maleimidocaproic acid, N-(5-Carboxypentyl)maleimide, N-Maleoyl-6-aminocaproic acid |
| CAS | 55750-53-3 |
| EINECS | 611-311-1 |
| InChI | InChI=1/C10H13NO4/c12-8-5-6-9(13)11(8)7-3-1-2-4-10(14)15/h5-6H,1-4,7H2,(H,14,15) |
| InChIKey | WOJKKJKETHYEAC-UHFFFAOYSA-N |
6-maleimidocaproic acid - Physico-chemical Properties
| Molecular Formula | C10H13NO4 |
| Molar Mass | 211.21 |
| Density | 1.285±0.06 g/cm3(Predicted) |
| Melting Point | 86-91°C |
| Boling Point | 407.3±28.0 °C(Predicted) |
| Flash Point | 200.1°C |
| Water Solubility | Soluble in water, methanol, ethanol, dimethyl sulfoxide. Insoluble in ether. |
| Solubility | DMSO (Slightly), Ethyl Acetate (Slightly) |
| Vapor Presure | 8.97E-08mmHg at 25°C |
| Appearance | Powder |
| Color | White to pale yellow |
| BRN | 1532405 |
| pKa | 4.74±0.10(Predicted) |
| Storage Condition | 2-8°C |
| Sensitive | Moisture Sensitive |
| Refractive Index | 1.536 |
| MDL | MFCD00043140 |
| Use | Probe for thiol groups (SH-groups) in membrane proteins.Intermediate for ester and amide linked maleimide monomers. |
6-maleimidocaproic acid - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R41 - Risk of serious damage to eyes R37/38 - Irritating to respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S39 - Wear eye / face protection. |
| WGK Germany | 3 |
| FLUKA BRAND F CODES | 10-21 |
| HS Code | 29251900 |
6-maleimidocaproic acid - Introduction
A sulfhydryl reactive heterobifunctional crosslinking reagent. A probe for thiol groups in proteins. Widely used probe for introducing maleimides groups into biomolecules. Spacer Arm: 9.4 Angstro
Last Update：2022-10-16 17:26:22
6-maleimidocaproic acid - Reference Information
| EPA chemical substance information | information provided by: ofmpeb.epa.gov (external link) |
| Application | 6-maleimidohexanoic acid is an acid derivative and can be used as a pharmaceutical intermediate. |
| Overview | 6-maleimidohexanoic acid is a surfactant, water-soluble bifunctional ligand. It can be prepared from 6-aminohexanoic acid and maleic anhydride in one step. |
Last Update：2024-04-10 22:29:15
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