6-mercapto-7-methylguanosine

6-mercapto-7-methylguanosine - Names and Identifiers

Name	7-METHYL-6-THIOGUANOSINE
Synonyms	MESG 7-METHYL-6-THIOGUANOSINE 7-Methyl-6-thio-D-guanosine 6-mercapto-7-methylguanosine 7-methyl-6-Thioguanosine (technical grade) 2-AMino-6-Mercapto-7-Methylpurine Ribonucleoside MESG [2-AMino-6-Mercapto-7-Methylpurine, inner salt] 2-AMino-6-Mercapto-7-Methyl-9-β-D-ribofuranosylpuriniuM Hydroxide, Inner Salt
CAS	55727-10-1

6-mercapto-7-methylguanosine - Physico-chemical Properties

Molecular Formula	C11H15N5H4S
Molar Mass	313.333
Melting Point	>175°C (dec.)
Storage Condition	-20°C Freezer, Under Inert Atmosphere
Use	Bioactive 7-Methyl-6-thioguanosine (MESG) is a chromogenic substrate that can be used for the quantification of inorganic phosphates. 7-Methyl-6-thioguanosine can also be used to determine the activity of purine nucleoside phosphorylase.

6-mercapto-7-methylguanosine - Introduction

7-methyll-6-thioguanosine (7-methyll-6-thioguanosine) is an organic compound with the molecular formula C11H15N5O4S. The following is a description of the nature, use, formulation and safety information of 7-methyll-6-thioguanosine:

Nature:
- 7-METHYL-6-THIOGUANOSINE is a solid compound, the common form is white crystals.
-Its melting point is between 220-223 ° C.
-7-methyll-6-thioguanosine is a relatively stable compound, but it will hydrolyze under strong alkaline conditions.

Use:
-7-methyll-6-thioguanosine is mainly used as a Biochemical reagent and is widely used in the fields of medicine and molecular biology.
-It is a substrate that lacks variability and can be used to determine enzyme activity, especially the activity of phosphotransferases (such as alkaline phosphatase).
- 7-METHYL-6-THIOGUANOSINE has also been used as a basic substrate for phosphatase inhibitors in pharmaceutical research.

Method:
The preparation of-7-METHYL-6-THIOGUANOSINE is usually carried out by synthetic chemical methods.
-A typical preparation method is to react 6-aminoguanine and 7-methylthiourea under alkaline conditions to produce 7-METHYL-6-THIOGUANOSINE.

Safety Information:
-7-methyll-6-thioguanosine is generally safer under normal use conditions, but the following matters still need to be paid attention:
-7-methyll-6-thioguanosine is a flammable substance, should avoid contact with fire, storage to avoid high temperature and open fire.
-Wear appropriate personal protective equipment, such as lab gloves and goggles, during operation.
-If you have inhaled or come into contact with 7-methyll-6-thioguanosine, immediately leave the contaminated area, wash off the contaminated skin, and seek medical attention for further treatment.

In General, 7-METHYL-6-THIOGUANOSINE is a commonly used Biochemical reagent that plays an important role in enzyme activity determination and phosphatase research. In use, attention should be paid to safe operation to avoid harm to the human body.

Last Update：2024-04-09 21:32:47