6014 2,4-DIFLUORO-3-CHLORO NITRO BENZENE

Name	3-chloro-2,4-difluoronitrobenzene
Synonyms	2,4-difluro-3-chloronitrobenzene 2,4-Difluoro-3-chloronitrobnzene 2,4-Difluoro-3-chlorobenzonitrile 3-CHLORO-2,4-DIFLUORONITROBENZENE 3-chloro-2,4-difluoronitrobenzene 2,4-DIFLUORO-3-CHLORONITROBENZENE 2,4-difluoro-3-chloronitrobenzene 2-chloro-1,3-difluoro-4-nitrobenzene 2-CHLORO-1,3-DIFLUORO-4-NITRO-BENZENE 6014 2,4-DIFLUORO-3-CHLORO NITRO BENZENE
CAS	3847-58-3
EINECS	411-980-8
InChI	InChI=1/C6H2ClF2NO2/c7-5-3(8)1-2-4(6(5)9)10(11)12/h1-2H

Risk Codes	R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. R50/53 - Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. R43 - May cause sensitization by skin contact R34 - Causes burns R22 - Harmful if swallowed
Safety Description	S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S61 - Avoid release to the environment. Refer to special instructions / safety data sheets. S60 - This material and its container must be disposed of as hazardous waste. S28 - After contact with skin, wash immediately with plenty of soap-suds. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S22 - Do not breathe dust.
UN IDs	1759
Hazard Note	Corrosive
Hazard Class	8
Packing Group	II

use	3-chloro-2, 4-difluoronitrobenzene is a pharmaceutical intermediate, and it has been reported in the literature that it can be used to prepare LSD1 inhibitors and selective HER2 inhibitors.
Preparation	Becher et al. reported that 3-chloro-2, 4-difluoronitrobenzene can be obtained by reacting 2,3, 4-trichloronitrobenzene with potassium fluoride.

Last Update：2024-04-09 21:01:54