7,12-diketolithocholic acid - Names and Identifiers
Name | 7,12-diketolithocholic acid
|
Synonyms | 7,12-DIKETO-LCA 7,12-diketo-LCA 7,12-dioxolitocholic acid 7,12-diketolithocholic acid Ursodeoxycholic Acid Impurity 13 5β-CHOLANIC acid-3α-OL-7, 12-DIONE 3-hydroxy-7,12-diketocholanoic acid Cholan-24-oic acid, 3-hydroxy-7,12-dioxo-, (3α,5β)- Cholic Acid IMpurity (3-alpha-Hydroxy-7,12-diketo-5-beta-cholan-24-oic acid) Cholic Acid Impurity 18 (3-alpha-Hydroxy-7,12-diketo-5-beta-cholan-24-oic acid)
|
CAS | 517-33-9
|
7,12-diketolithocholic acid - Physico-chemical Properties
Molecular Formula | C24H36O5
|
Molar Mass | 404.54 |
Density | 1.176±0.06 g/cm3(Predicted) |
Melting Point | 190-192 °C(Solv: acetone (67-64-1)) |
Boling Point | 582.2±50.0 °C(Predicted) |
Solubility | Methanol (Slightly), Water (Slightly) |
Appearance | Solid |
Color | White to Off-White |
pKa | 4.74±0.10(Predicted) |
Storage Condition | Hygroscopic, Refrigerator, under inert atmosphere |
7,12-diketolithocholic acid - Introduction
7,12-diketolithocholic acid(7,12-diketolithocholic acid) is a bile acid compound. It has the following properties:
1. Chemical properties: 7,12-diketolithocholic acid is a yellow crystal with chemical instability. It is sensitive to light and heat and readily degrades under oxidative conditions.
2. Biological activity: 7,12-diketolithocholic acid has anti-inflammatory effects in the body, and is considered to be an important factor in regulating lipid metabolism, and has certain effects on cholesterol metabolism and cholesterol stones.
3. Application: Due to its unique structure and biological activity, 7,12-diketolithocholic acid is widely used in the field of medicine research, especially for the treatment of gallbladder diseases and cholesterol metabolism related diseases.
4. Preparation method: 7,12-diketolithocholic acid can be obtained by oxidizing rock peak acid (lithocholic acid) under specific conditions, or synthesized by synthetic chemical methods.
5. Security information: The security information about 7,12-diketolithocholic acid is currently relatively limited, so you should be cautious when using it. Due to its chemical instability, prolonged exposure to light and heat conditions should be avoided. At the same time, the compound should be handled and used in accordance with laboratory practices and safety guidelines.
Last Update:2024-04-09 21:11:58