7-AMINO-2,3-DIHYDRO-INDOLE-1-CARBOXYLIC ACID TERT-BUTYL ESTER - Names and Identifiers
Name | 1H-Indole-1-carboxylicacid, 7-amino-2,3-dihydro-, 1,1-dimethylethyl ester
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Synonyms | 1-Boc-7-aminoindoline tert-Butyl 7-aMinoindoline-1-carboxylate tert-butyl 7-amino-2,3-dihydroindole-1-carboxylate tert-Butyl 7-amino-2,3-dihydro-1H-indole-1-carboxylate 7-Amino-2,3-Dihydro-Indole-1-Carboxylic Acid Tert-Butyl Ester 7-AMINO-2,3-DIHYDRO-INDOLE-1-CARBOXYLIC ACID TERT-BUTYL ESTER 1H-Indole-1-carboxylicacid, 7-amino-2,3-dihydro-, 1,1-dimethylethyl ester 1H-Indole-1-carboxylic acid, 7-amino-2,3-dihydro-, 1,1-dimethylethyl ester 1H-Indole-1-carboxylic acid, 7-aMino-2,3-dihydro-, 1,1-diMethylethyl ester
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CAS | 885272-44-6
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7-AMINO-2,3-DIHYDRO-INDOLE-1-CARBOXYLIC ACID TERT-BUTYL ESTER - Physico-chemical Properties
Molecular Formula | C13H18N2O2
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Molar Mass | 234.29 |
Density | 1.177±0.06 g/cm3(Predicted) |
Boling Point | 357.7±41.0 °C(Predicted) |
pKa | 4.94±0.20(Predicted) |
Storage Condition | 2-8°C |
7-AMINO-2,3-DIHYDRO-INDOLE-1-CARBOXYLIC ACID TERT-BUTYL ESTER - Introduction
1H-Indole-1-carboxylicacid, 7-amino-2,3-dihydro-, 1,1-dimethylethyl ester is a chemical compound with the chemical formula C14H18N2O2. It is a derivative of indole with a beccol (Boc) protecting group and an amine functional group. The following is an introduction to some of its properties, uses, methods and safety information:
properties: 1H-indole-1-carboxylicacid, 7-amino-2,3-dihydro-, 1,1-dimethylethyl ester is a colorless or slightly yellow solid with a faint ammonia odor. It is soluble in some organic solvents such as chloroform, dimethylformamide and dichloromethane.
use: 1H-indole-1-carboxylicacid, 7-amino-2,3-dihydro-, 1,1-dimethylethyl ester is a commonly used organic synthesis intermediate, commonly used in the synthesis of indole compounds. It can be carried out by Boc protection of indole, followed by nucleophilic substitution reaction, removal of the protecting group to obtain the target compound.
Preparation method: 1H-Indole-1-Carboxylicacid, 7-amino-2,3-dihydro-, 1,1-dimethylethyl ester can be prepared by reacting 7-aminoindole with Boc anhydride. The reaction is usually carried out in an organic solvent at room temperature or under heating to give 1H-Indole-1-carboxylicacid, 7-amino-2,3-dihydro-, 1,1-dimenthylethyl ester.
Safety information: Limited safety information regarding 1H-Indole-1-carboxylicacid, 7-amino-2,3-dihydro-, 1,1-dimethylethyyl ester. Since it is a chemical, general laboratory safety practices should be followed, such as wearing appropriate protective gloves and glasses. In addition, the compound should be stored and handled properly to avoid skin contact and inhalation, and away from fire and high temperatures. Harmful dust or gas should also be avoided during use. If necessary, operate under appropriate facilities and in accordance with the relevant Safety Data Sheet (SDS).
Last Update:2024-04-10 22:29:15