7-Deaza-2'-deoxyadenosine
7-(2-deoxy-D-erythro-pentofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine
CAS: 60129-59-1
Molecular Formula: C11H14N4O3
7-Deaza-2'-deoxyadenosine - Names and Identifiers
| Name | 7-(2-deoxy-D-erythro-pentofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine |
| Synonyms | deoxytubercidin 2'-DEOXYTUBERCIDIN 7-deazadeoxyadenosine 7-Deaza-2'-deoxyadenosine 7-DEAZA-2'-DEOXYADENOSINE 7-(2-deoxy-D-erythro-pentofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine 3-d)pyrimidin-4-amine,7-(2-deoxy-beta-d-erythro-pentofuranosyl)-7h-pyrrolo( 7h-pyrrolo(2,3-d)pyrimidine,4-amino-7-(2-deoxy-beta-d-erythro-pentofuranosyl 7-(2-deoxy-beta-d-erythro-pentofuranosyl)-7h-pyrrolo(2,3-d)pyrimidin-4-amine (2R,3S,5R)-5-(4-Amino-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol |
| CAS | 60129-59-1 |
| EINECS | 1592732-453-0 |
| InChI | InChI=1/C11H14N4O3/c12-10-6-1-2-15(11(6)14-5-13-10)9-3-7(17)8(4-16)18-9/h1-2,5,7-9,16-17H,3-4H2,(H2,12,13,14)/t7-,8+,9?/m0/s1 |
7-Deaza-2'-deoxyadenosine - Physico-chemical Properties
| Molecular Formula | C11H14N4O3 |
| Molar Mass | 250.25 |
| Density | 1.75 |
| Melting Point | >217°C (dec.) |
| Boling Point | 601℃ |
| Flash Point | 318℃ |
| Solubility | DMSO (Slightly, Heated), Methanol (Slightly, Heated, Sonicated) |
| Vapor Presure | 2.62E-15mmHg at 25°C |
| Appearance | Solid |
| Color | White to Pale Yellow |
| Storage Condition | 2-8°C |
| Refractive Index | 1.797 |
7-Deaza-2'-deoxyadenosine - Introduction
The 7-(+)-7H-pyrrolo[2,3-d]pyrimidin-4-amine, also known as the 7-(+)-7H-pyrrolo[2,3-d]pyrimidin-4-amine, is an organic compound that belongs to the class of adenosine analogs.
Nature:
-Appearance: 7-(1)-7H-cryrolo [2,3-d]pyrimidin-4-amine is a colorless crystalline solid, or white to light yellow powder.
-Solubility: Poor solubility in water, slightly soluble in alcohols and some organic solvents.
-Thermal stability: It can be decomposed when the temperature is high.
Use:
7-rolo [2,3-d]pyrimidin-4-amine have important applications in biochemistry and medicinal chemistry:
-As nucleoside analogs: can be used to synthesize mimics of specific positions in DNA or RNA sequences. It can be used as a tool molecule in the study of nucleotides.
-Antiviral activity: 7-(-)-7H-Pyrrolo [2,3-d]pyrimidin-4-amine has antiviral activity, especially has a certain inhibitory effect on hepatitis B virus.
-Drug research: Due to its unique chemical structure, 7-(g)-7H-cryrolo [2,3-d]pyrimidin-4-amine can also be used to discover new biologically active compounds in drug research.
Preparation Method:
7-(Br)-7H-Pyrlo [2,3-d]pyrimidin-4-amine preparation methods mainly include chemical synthesis and enzymatic reaction.
-Chemical synthesis method: Through a series of organic synthesis reactions, appropriate raw materials are converted into the desired target compounds.
-Enzyme catalysis: Using the catalysis of the enzyme, under suitable conditions, the suitable substrate is converted into 7-(1-d)-7H-pyrrolo[2,3-] pyrimidin-4-amine. This method is often used in research laboratories.
Safety Information:
Limited safety information is available on the 7-(but)-7H-chrrolo [2,3-d]pyrimidin-4-amine. As a chemical, it may be toxic to humans. When using or handling, should follow the appropriate safety guidelines, avoid inhalation, intake or skin contact. Further toxicological studies and safety assessments are necessary.
Nature:
-Appearance: 7-(1)-7H-cryrolo [2,3-d]pyrimidin-4-amine is a colorless crystalline solid, or white to light yellow powder.
-Solubility: Poor solubility in water, slightly soluble in alcohols and some organic solvents.
-Thermal stability: It can be decomposed when the temperature is high.
Use:
7-rolo [2,3-d]pyrimidin-4-amine have important applications in biochemistry and medicinal chemistry:
-As nucleoside analogs: can be used to synthesize mimics of specific positions in DNA or RNA sequences. It can be used as a tool molecule in the study of nucleotides.
-Antiviral activity: 7-(-)-7H-Pyrrolo [2,3-d]pyrimidin-4-amine has antiviral activity, especially has a certain inhibitory effect on hepatitis B virus.
-Drug research: Due to its unique chemical structure, 7-(g)-7H-cryrolo [2,3-d]pyrimidin-4-amine can also be used to discover new biologically active compounds in drug research.
Preparation Method:
7-(Br)-7H-Pyrlo [2,3-d]pyrimidin-4-amine preparation methods mainly include chemical synthesis and enzymatic reaction.
-Chemical synthesis method: Through a series of organic synthesis reactions, appropriate raw materials are converted into the desired target compounds.
-Enzyme catalysis: Using the catalysis of the enzyme, under suitable conditions, the suitable substrate is converted into 7-(1-d)-7H-pyrrolo[2,3-] pyrimidin-4-amine. This method is often used in research laboratories.
Safety Information:
Limited safety information is available on the 7-(but)-7H-chrrolo [2,3-d]pyrimidin-4-amine. As a chemical, it may be toxic to humans. When using or handling, should follow the appropriate safety guidelines, avoid inhalation, intake or skin contact. Further toxicological studies and safety assessments are necessary.
Last Update：2024-04-09 02:00:47
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CAS: 60129-59-1
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Multiple Specifications
Product Name: 7-Deaza-2'-deoxyadenosine Request for quotationCAS: 60129-59-1
Tel: +86-571-88162785
Email: Lucy@verypharm.com
Mobile: +86-13606544505
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