Name | DRACORHODIN PEROCHLORATE |
Synonyms | BRN 1977317 Dracorhodin perchlorate Dracohodin perochlorate DRACORHODIN PEROCHLORATE 7-Hydroxy-5-methoxy-6-methyl-2-phenyl-1-benzopyrylium perchlorate |
CAS | 125536-25-6 |
InChI | InChI=1/C17H14O3/c1-11-14(18)10-16-13(17(11)19-2)8-9-15(20-16)12-6-4-3-5-7-12/h3-10H,1-2H3/p+1 |
Molecular Formula | C17H15ClO7 |
Molar Mass | 366.75 |
Solubility | Soluble in methanol |
Appearance | Orange yellow crystalline powder |
Color | Very Dark Orange |
Storage Condition | Amber Vial, -20°C Freezer, Under inert atmosphere |
Stability | Moisture Sensitive |
MDL | MFCD07781413 |
Physical and Chemical Properties | Orange-yellow crystalline powder, soluble in methanol, derived from Dragon's blood. |
Reference Show more | 1. Wu Yaling, Tang Xinhong, Chen Gangquan. Role of dracorhodin perchlorate in regulating proliferation and wound healing of fibroblasts [J]. Genomics and applied biology, 2018,37(10):4711-4716. 2. Jiang, Xiaowen, et al. "Dracorhodin perchlorate regulates fibroblast proliferation to promote rat's wound healing." Journal of pharmacological sciences 136.2 (2018): 66-72.https:// doi.org/10.1016/j.jphs. 2017.12.003 3. Lu, Zhengyang, et al. "Dracorhodin perchlorate induces apoptosis and G2/M cell cycle arrest in human esophageal squamous cell carcinoma through inhibition of the JAK2/STAT3 and AKT/FOXO3a pathways." Molecular medicine reports 20.3 (2019): 2091-2100.https:/ 4. [IF=2.835] Xiaowen Jiang et al."Dracorhodin perchlorate regulates fibroblast proliferation to promote rat's wound healing."J Pharmacol Sci. 2018 Feb;136:66 5. [IF=1.851] Zhengyang Lu et al."Dracorhodin perchlorate induces apoptosis and G2/M cell cycle arrest in human esophageal squamous cell carcinoma through inhibition of the JAK2/STAT3 and AKT/FOXO3a pathways."Mol Med Rep. 2019 Sep;20(3):2091-2100 |
overview | dracorin perchlorate induces apoptosis in human cervical cancer HeLa cells. MTT assay was used to determine the cytotoxic effect of dracorhodin perchlorate on HeLa cells. |
biological activity | Dracorhodin perchlorate (Dracohodin perochlorate) is a natural product derived from the natural drug dragon's blood. Dracorhodin perchlorate can inhibit cell proliferation and induce cell cycle arrest and apoptosis. |
use | dracorhodin perchlorate has the effects of preventing and treating diabetes, nephropathy and anti-tumor. |