7-aminoquinazoline-2,4(1H,3H)-dione

7-aminoquinazoline-2,4(1H,3H)-dione - Names and Identifiers

Name	7-aminoquinazoline-2,4(1H,3H)-dione
Synonyms	7-Aminoquinazoline-2,4(1H,3H) 7-aminoquinazoline-2,4(1H,3H)-dione 7-aMinoquinazoline-2,4(1H,3H)-dione 2,4(1H,3H)-Quinazolinedione, 7-amino-
CAS	59674-85-0

7-aminoquinazoline-2,4(1H,3H)-dione - Physico-chemical Properties

Molecular Formula	C8H7N3O2
Molar Mass	177.16
Melting Point	320℃
Storage Condition	Keep in dark place,Inert atmosphere,Room temperature

7-aminoquinazoline-2,4(1H,3H)-dione - Introduction

7-aminoquinazoline-2,4(1H,3H)-dione is an organic compound with the chemical formula C8H5N3O2. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: 7-aminoquinazoline-2,4(1H,3H)-dione is white or off-white crystalline powder.
-Melting point: The melting point range is generally between 220°C and 224°C.
-Solubility: Soluble in common organic solvents such as ethanol, dimethylformamide and dichloromethane.

Use:
-Drugs: 7-aminoquinazoline-2,4(1H,3H)-dione and its derivatives have potential drug activities, such as inhibitory effects on certain cancer cells, and may be used in the development of anti-tumor drugs.
-Chemical reagent: It can be used as a starting material or intermediate for the construction of organic molecular framework in organic synthesis, and is used for the synthesis of other organic compounds.

Preparation Method:
-A common synthesis method is through the reaction of o-nitrophenol and ammonia.
-The specific step is to first react o-nitrophenol with an acidic solution to generate nitrophenolate, and then reduce it to obtain p-aminophenol. The p-aminophenol then undergoes a ring closure reaction to give 7-aminoquinazoline-2,4(1H,3H)-dione.

Safety Information:
- 7-aminoquinazoline-2,4(1H,3H)-dione is not particularly hazardous under normal laboratory operating conditions.
-During use and handling, basic laboratory safety measures should be taken, such as wearing gloves and goggles, and avoiding contact with skin and eyes.
-It should be stored in a dry, sealed container, avoid contact with strong oxidants, and away from fire and heat sources.

Last Update：2024-04-09 02:00:47