7-ketolithocholic Methyl ester - Names and Identifiers
7-ketolithocholic Methyl ester - Physico-chemical Properties
Molecular Formula | C25H40O4
|
Molar Mass | 404.5827 |
Density | 1.085±0.06 g/cm3(Predicted) |
Melting Point | 107-109℃ |
Boling Point | 505.7±25.0 °C(Predicted) |
pKa | 15.02±0.70(Predicted) |
Storage Condition | 2-8°C |
7-ketolithocholic Methyl ester - Upstream Downstream Industry
7-ketolithocholic Methyl ester - Introduction
7-ketolitholic Methyl ester, also known as 7-ketomethyl ester hydrochloride cholate, is an organic compound. The following is an introduction to the nature, use, preparation and safety information of 7-ketolitholic Methyl ester:
Nature:
The chemical formula of 7-ketolitholic Methyl ester is C25H40O4, and the relative molecular mass is 396.58g/mol. It is a white to pale yellow crystalline solid with a distinctive odor. It can be dissolved in organic solvents such as ethanol and dichloromethane, but has low solubility in water.
Use:
7-ketolitholic Methyl ester is widely used in the pharmaceutical industry. It is an important intermediate for the synthesis of various drugs, including cholesterol metabolism regulators and anti-tumor drugs. Its chemical structure makes it have the ability to inhibit cholesterol synthesis and regulate cholesterol metabolism.
Method:
There are many preparation methods of 7-ketolitholic Methyl ester. One of the common methods is to react obeticholic acid with iminodimethanol to obtain iminocholic acid ethyl ester, the 7-ketolitholic Methyl ester is formed by hydrogen bond cleavage and acid-catalyzed reaction.
Safety Information:
7-ketolitholic Methyl ester is a chemical substance, and the following safety precautions should be paid attention to when using it:
1. Wear suitable personal protective equipment during operation, including anti-glasses, protective gloves and protective clothing to prevent contact with skin or inhalation.
2. When using, avoid inhaling its dust or solvent vapor, and operate in a well-ventilated place.
3. Avoid contact with strong oxidants or strong acids to prevent fire or explosion.
4. If you ingest or come into contact with 7-ketolitholic Methyl ester, you should seek medical advice immediately and bring the safety data sheet of the substance.
Last Update:2024-04-09 19:05:54