7387-57-7

7387-57-7 - Names and Identifiers

Name	2',3',5'-tri-O-acetyladenosine
Synonyms	NSC 76766 Nsc 76766 Tri-O-acetyladenosine 2,3,5-TRIACETYLADENOSINE -Tri-O-acetyl-D-adenosine Adenosine, 2',3',5'-triacetate 2',3',5'-tri-O-acetyladenosine 2',3',5'-TRI-O-ACETYLADENOSINE 2',3',5'-Tri-O-acetyl adenosine 2',3',5'-Tri-O-acetyl-D-adenosine 2',3',5'-Tri-O-Acetyl-D-Adenosine 6-aMino-9-[(2,3,5-tri-O-acetyl)-β-D-ribofuranosyl]purine
CAS	7387-57-7
InChI	InChI=1/C16H19N5O7/c1-7(22)25-4-10-12(26-8(2)23)13(27-9(3)24)16(28-10)21-6-20-11-14(17)18-5-19-15(11)21/h5-6,10,12-13,16H,4H2,1-3H3,(H2,17,18,19)/t10-,12-,13-,16-/m1/s1

7387-57-7 - Physico-chemical Properties

Molecular Formula	C16H19N5O7
Molar Mass	393.35
Density	1.62±0.1 g/cm3(Predicted)
Melting Point	168-170°C
Boling Point	594.1±60.0 °C(Predicted)
Flash Point	313.1°C
Solubility	Chloroform (Sparingly), DMSO (Slightly), Methanol (Sparingly)
Vapor Presure	4.41E-14mmHg at 25°C
Appearance	Solid
Color	White to Off-White
pKa	3.82±0.10(Predicted)
Storage Condition	Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
Refractive Index	1.679

7387-57-7 - Risk and Safety

Safety Description	24/25 - Avoid contact with skin and eyes.
WGK Germany	3
HS Code	29349990

7387-57-7 - Introduction

2 ',3',5 '-tri-O-acetyladenosine is a naturally occurring nucleoside compound having the formula C17H23N5O8. It consists of adenosine 2, 3 and 5 carbon atoms of the hydroxyl group is replaced by acetyl.

2 ',3',5 '-tri-O-acetyladenosine is a white or off-white crystalline powder with good solubility. It is highly soluble in water, soluble in ethanol and chloroform, but insoluble in ether.

In biology, 2 ',3',5 '-tri-O-acetyladenosine are often used as agonists or inhibitors of adenosine receptors. In addition, it can also be used as a synthetic intermediate for hormones, as well as a raw material for drug research and development in the field of biomedicine.

From the viewpoint of chemical synthesis, 2 ',3',5 '-tri-O-acetyladenosine is generally prepared by reacting adenosine with an appropriate amount of acetic anhydride in an appropriate solvent and temperature. During the preparation process, attention should be paid to the control of reaction temperature and time, as well as other reaction conditions.

Regarding safety information, according to current scientific research, 2 ',3',5 '-tri-O-acetyladenosine are relatively safe within the general concentration range. However, if the eyes or skin are touched, rinse immediately with plenty of water and seek medical help. At the same time, the use of this compound should follow laboratory safety practices and maintain proper ventilation conditions. During storage and transportation, contact with oxidants and combustibles should be avoided to ensure safety.

Last Update：2024-04-09 21:11:58