8-bromoquinolin-2(1H)-one
8-bromoquinolin-2(1H)-one
CAS: 67805-67-8
Molecular Formula: C9H6BrNO
8-bromoquinolin-2(1H)-one - Names and Identifiers
| Name | 8-bromoquinolin-2(1H)-one |
| Synonyms | 8-bromoquinolin-2-ol 8-Bromo-2(1H)-quinolinone 8-BROMOQUINOLIN-2(1H)-ONE 8-Bromo-1H-quinolin-2-one 8-bromoquinolin-2(1H)-one 8-BroMoquinoline-2(1h)-one 8-Bromo-2-hydroxyquinoline 8-Bromo-1,2-dihydroquinolin-2-one 8-Bromo-1,2-dihydro-2-oxoquinoline |
| CAS | 67805-67-8 |
| InChI | InChI=1/C9H6BrNO/c10-7-3-1-2-6-4-5-8(12)11-9(6)7/h1-5H,(H,11,12) |
8-bromoquinolin-2(1H)-one - Physico-chemical Properties
| Molecular Formula | C9H6BrNO |
| Molar Mass | 224.05 |
| Density | 1.620±0.06 g/cm3(Predicted) |
| Melting Point | 196-198 °C |
| Boling Point | 390.2±42.0 °C(Predicted) |
| Flash Point | 189.813°C |
| Vapor Presure | 0mmHg at 25°C |
| pKa | 10.70±0.70(Predicted) |
| Storage Condition | Room temperature. |
| Refractive Index | 1.63 |
8-bromoquinolin-2(1H)-one - Introduction
8-bromoquinolin-2(1H)-one is an organic compound with the formula C9H6BrNO and a molecular weight of 230.05g/mol. The following is an introduction to its nature, use, preparation and safety information:
Nature:
- 8-bromoquinolin-2(1H)-one is a white crystalline solid, stable at room temperature.
-it has good solubility, soluble in organic solvents such as methanol, dichloromethane and ethanol.
-The compound has a cigarette taste and bitterness.
Use:
- 8-bromoquinolin-2(1H)-one has certain applications in the field of medicine. It is an important synthetic intermediate, commonly used in the synthesis of other compounds containing quinoline skeleton.
-Quinoline compounds have a wide range of applications in the field of medicine, can be used for the synthesis of antiviral, anti-inflammatory, anti-tumor drugs.
Preparation Method:
The preparation method of -8-bromoquinolin-2(1H)-one is usually obtained by reacting quinoline bromide and quinone under alkaline conditions. The specific process is as follows:
The quinoline bromide and quinone are dissolved in an alkaline medium, and after a period of reaction, the target product is obtained by acidification and crystallization purification.
Safety Information:
- 8-bromoquinolin-2(1H)-one is an organic compound and appropriate laboratory and protective measures should be taken.
-The substance may cause irritation to the eyes, skin and respiratory tract and should be handled with appropriate protective equipment such as chemical goggles, gloves and respiratory protection.
-During storage and handling, care should be taken to avoid mixing with oxidants and strong bases to avoid dangerous reactions.
-Please read the relevant safety data sheets carefully when using and storing, and follow the correct operating procedures.
Nature:
- 8-bromoquinolin-2(1H)-one is a white crystalline solid, stable at room temperature.
-it has good solubility, soluble in organic solvents such as methanol, dichloromethane and ethanol.
-The compound has a cigarette taste and bitterness.
Use:
- 8-bromoquinolin-2(1H)-one has certain applications in the field of medicine. It is an important synthetic intermediate, commonly used in the synthesis of other compounds containing quinoline skeleton.
-Quinoline compounds have a wide range of applications in the field of medicine, can be used for the synthesis of antiviral, anti-inflammatory, anti-tumor drugs.
Preparation Method:
The preparation method of -8-bromoquinolin-2(1H)-one is usually obtained by reacting quinoline bromide and quinone under alkaline conditions. The specific process is as follows:
The quinoline bromide and quinone are dissolved in an alkaline medium, and after a period of reaction, the target product is obtained by acidification and crystallization purification.
Safety Information:
- 8-bromoquinolin-2(1H)-one is an organic compound and appropriate laboratory and protective measures should be taken.
-The substance may cause irritation to the eyes, skin and respiratory tract and should be handled with appropriate protective equipment such as chemical goggles, gloves and respiratory protection.
-During storage and handling, care should be taken to avoid mixing with oxidants and strong bases to avoid dangerous reactions.
-Please read the relevant safety data sheets carefully when using and storing, and follow the correct operating procedures.
Last Update：2024-04-09 20:49:11
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Product Name: 8-BROMOQUINOLIN-2(1H)-ONE Visit Supplier Webpage Request for quotation
CAS: 67805-67-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 67805-67-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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